DisGeNET - a database of gene-disease associations

Hereditary Nonpolyposis Colorectal Neoplasms, C0009405

Variant: rs1114167767 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1114167767

MSH6 ; FBXO11

0.700

CausalMutation

CLINVAR

Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel.

26687385

2016

dbSNP:

rs1114167767

MSH6 ; FBXO11

0.700

CausalMutation

CLINVAR

Yield of routine molecular analyses in colorectal cancer patients ≤70 years to detect underlying Lynch syndrome.

22081473

2012

dbSNP:

rs1114167767

MSH6 ; FBXO11

0.700

CausalMutation

CLINVAR

Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.

21642682

2011