Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7756992
rs7756992
CDKAL1
0.900 GeneticVariation BEFREE In a simple linear regression model, expression of CDKAL1-v1 was associated with the lead type 2 diabetes-associated SNP, rs7756992, in whole blood and islets. 25634229

2015
dbSNP: rs7756992
rs7756992
CDKAL1
G 0.900 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016
dbSNP: rs7756992
rs7756992
CDKAL1
0.900 GeneticVariation BEFREE HbA1c reduction after use of DPP-4 inhibitors for 3 months was significantly greater in patients with a risk allele for type 2 diabetes (GG -0.4%, CG -0.5%, CC -0.8%, p = 0.02 for rs7754840 and AA -0.4%, AG -0.5%, GG -0.8%, p = 0.01 for rs7756992). 27139004

2016
dbSNP: rs7756992
rs7756992
CDKAL1
0.900 GeneticVariation BEFREE CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes. 28821857

2017
dbSNP: rs7756992
rs7756992
CDKAL1
0.900 GeneticVariation BEFREE However, no significant association was detected between HHEX (rs1111875), CDKAL1 (rs7756992), or UBE2E2 (rs7612463) and T2D. 29871606

2018
dbSNP: rs7756992
rs7756992
CDKAL1
G 0.900 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs7756992
rs7756992
CDKAL1
0.900 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019