DisGeNET - a database of gene-disease associations

Diabetic Nephropathy, C0011881

Variant: rs10823108 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs10823108

SIRT1

0.020

GeneticVariation

BEFREE

Mutation genotype GG and GG + AG in the rs10823108 locus can increase the risk of DKD.

30110438

2018

dbSNP:

rs10823108

SIRT1

0.020

GeneticVariation

BEFREE

In conclusion, genetic variant rs10823108 in SIRT1 and variant rs17446614 in FoxO1 may contribute to the risk of DN in T2DM patients.

28860538

2017