|
rs268
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conclude that carriers of N291S or combined D9N/ - 93T --> G mutations in the LPL gene are at substantially increased risk of pre-eclampsia.
|
10636447 |
1999 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We genotyped a total of 171 cases with preeclampsia or eclampsia and 185 normotensive control subjects for the methylenetetrahydrofolate reductase (MTHFR) 677 C --> T genotype.
|
10655155 |
2000 |
|
rs5370
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Lys198Asn polymorphism does not directly contribute to the incidence of pre-eclampsia.
|
11593097 |
2001 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Our study shows that the M235T variant in the gene encoding angiotensinogen could be a risk factor in mild and severe pre-eclampsia.
|
12417054 |
2003 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Association of pre-eclampsia with hyperhomocysteinaemia and methylenetetrahydrofolate reductase gene C677T polymorphism in a Turkish population.
|
15387863 |
2004 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Among these are the angiotensinogen (AGT) gene variant Met235Threo, which has been associated with pre-eclampsia and the endothelial nitric oxide synthase (eNOS) polymorphism Glu298Asp, which has been associated with both pre-eclampsia and abruptio placentae, a condition that often co-exists with pre-eclampsia.
|
16059745 |
2005 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
No association was demonstrated between the M235T variant of the AGT gene and pre-eclampsia or abruptio placentae.
|
16059745 |
2005 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Methylenetetrahydrofolate reductase C677T polymorphism and Factor V Leiden variant in Mexican women with preeclampsia/eclampsia.
|
15905108 |
2005 |
|
rs1177506410
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among these are the angiotensinogen (AGT) gene variant Met235Threo, which has been associated with pre-eclampsia and the endothelial nitric oxide synthase (eNOS) polymorphism Glu298Asp, which has been associated with both pre-eclampsia and abruptio placentae, a condition that often co-exists with pre-eclampsia.
|
16059745 |
2005 |
|
rs1275805226
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among these are the angiotensinogen (AGT) gene variant Met235Threo, which has been associated with pre-eclampsia and the endothelial nitric oxide synthase (eNOS) polymorphism Glu298Asp, which has been associated with both pre-eclampsia and abruptio placentae, a condition that often co-exists with pre-eclampsia.
|
16059745 |
2005 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We investigated the role of eNOS T-786C, G894T and 4a4b polymorphisms in predisposing to both pre-eclampsia and the recurrence of negative pregnancy events, per se and in the presence of angiotensin-converting enzyme (ACE) DD genotype, and investigated their influence on maternal-fetal flow in 106 non-thrombophilic women with a history of pre-eclampsia, compared with 106 women with a history of normal pregnancy.
|
16915032 |
2006 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The angiotensinogen M235T polymorphism might contribute to the multifactorial pathogenesis of gestational hypertension and pre-eclampsia.
|
17563539 |
2007 |
|
rs1267969615
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The angiotensinogen M235T polymorphism might contribute to the multifactorial pathogenesis of gestational hypertension and pre-eclampsia.
|
17563539 |
2007 |
|
rs779370907
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of four SNPs were observed, of which two (G300A exon 8 and G274T exon 16) showed statistically significant association with pre-eclampsia.
|
17991113 |
2007 |
|
rs780972489
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of four SNPs were observed, of which two (G300A exon 8 and G274T exon 16) showed statistically significant association with pre-eclampsia.
|
17991113 |
2007 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The well-known M268T [M235T] polymorphism was not associated with pre-eclampsia.
|
18645251 |
2008 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In all, 17 studies (including 1446 cases and 3829 controls) published in English between 1993 and October 2006 on the association of angiotensinogen gene M235T polymorphism with preeclampsia/eclampsia were selected.
|
18698203 |
2008 |
|
rs11549465
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here we studied whether two single nucleotide sequence variants, c.1744 C>T that changes residue 582 of HIF-1alpha from proline to serine (P582S) and c.1762 G>A that changes residue 588 of HIF-1alpha from alanine to threonine (A588T) in the exon 12 of the HIF1A gene, are associated with pre-eclampsia.
|
18980686 |
2008 |
|
rs11549467
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here we studied whether two single nucleotide sequence variants, c.1744 C>T that changes residue 582 of HIF-1alpha from proline to serine (P582S) and c.1762 G>A that changes residue 588 of HIF-1alpha from alanine to threonine (A588T) in the exon 12 of the HIF1A gene, are associated with pre-eclampsia.
|
18980686 |
2008 |
|
rs2536512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest a role of SOD3 Ala40Thr single nucleotide polymorphism in the risk of severe fetal growth restriction-complicated pre-eclampsia.
|
19108943 |
2009 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
As observed in this study Glu298Asp eNOS gene polymorphism did not showed significant association with pre-eclampsia.
|
20047583 |
2010 |
|
rs1341667
|
|
|
0.020 |
GeneticVariation |
BEFREE |
By using complementary in vitro and ex vivo approaches, we show that the risk allele (Y153H) of the pre-eclampsia susceptibility gene STOX1 negatively regulates trophoblast invasion by upregulation of the cell-cell adhesion protein alpha-T-catenin (CTNNA3).
|
20400461 |
2010 |
|
rs2890565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results of this study suggest that UTS2 single gene (S89N) polymorphism is not associated with pre-eclampsia.
|
20653105 |
2010 |
|
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Glu298Asp polymorphism in the eNOS gene could be an individual's risk factor and may modulate progression to an eclampsia complication of preeclampsia in the Turkish population.
|
21793998 |
2011 |
|
rs699
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We evaluated the association of the mutated genotypes Met235Thr-AGT, Thr174Met-AGT, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123A-AT2R2, (83)A/G-REN with the risk and outcome of pre-eclampsia; we also investigated whether genes in newborns increase maternal risk of pre-eclampsia.
|
21436209 |
2011 |