The results demonstrated that WNT4 rs2235529 is associated with endometriosisin Chinese Han women, which may result in aberrant expression of WNT4, leading to the pathogenesis of endometriosis.
This might constitute the first step towards identifying polymorphism combinations that predispose to endometriosis (IFNG (CA) repeat, GSTM1 null genotype, GSTP1 rs1695, WNT4 rs16826658 and WNT4 rs2235529) in a large cohort of patients with well-defined inclusion criteria.