Gene: TP53 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs878854066
rs878854066
TP53
0.070 GeneticVariation BEFREE In stratified analyses by ethnicity, source of controls, and glioma subtypes, the p53 codon 72 Arg/Pro polymorphism did not alter the risk for glioma in population-based, hospital-based, astrocytoma, and oligodendroglioma studies among Caucasian. 23860773

2013
dbSNP: rs878854066
rs878854066
TP53
0.070 GeneticVariation BEFREE In conclusion, our meta-analysis, based on the combined data from published papers before May 2013, reveals no evidence for significant association between p53 Arg72Pro polymorphism and glioma risk. 24488625

2014
dbSNP: rs878854066
rs878854066
TP53
0.070 GeneticVariation BEFREE Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma. 23096687

2012
dbSNP: rs878854066
rs878854066
TP53
0.070 GeneticVariation BEFREE These findings suggest that the pri-miR-34b/c rs4938723CC and TP53 Arg72-Pro polymorphisms may be associated with the risk of glioma. 30319976

2018
dbSNP: rs878854066
rs878854066
TP53
0.070 GeneticVariation BEFREE In this first assessment of the role of TP53 Arg72Pro polymorphism in a large series of Portuguese glioma tumors, no association was observed with glioma susceptibility or overall survival, except for patients submitted to adjuvant therapy. 18068527

2008
dbSNP: rs878854066
rs878854066
TP53
0.070 GeneticVariation BEFREE Our data suggest that TP53 Pro47Ser and Arg72Pro SNPs are not involved either in susceptibility to developing gliomas or in patient survival, at least in the Brazilian population. 18393224

2008
dbSNP: rs121912660
rs121912660
TP53
0.010 GeneticVariation BEFREE Our observations indicate that the R280T mutation of p53 regulates the proliferation of human glioma cells related to the GSK-3β/PTEN pathway. 22999923

2012
dbSNP: rs1625895
rs1625895
TP53
0.010 GeneticVariation BEFREE Six hundred and eighty glioma cases (298 glioblastoma (GBM)), 503 meningioma cases, and 1555 controls recruited in the Nordic-UK Interphone study, were analysed in association with three polymorphisms in p53 (rs2287499, rs1042533, rs1625895) and five polymorphisms in ATM ( rs228599, rs3092992, rs664143, rs170548, rs3092993). 17151932

2007
dbSNP: rs1642785
rs1642785
TP53
0.010 GeneticVariation BEFREE The codon 72 variant (rs1042522) and rs1642785 polymorphisms possibly poses risk to glioma development in Indian population. 21115003

2011
dbSNP: rs1800371
rs1800371
TP53
0.010 GeneticVariation BEFREE Our data suggest that TP53 Pro47Ser and Arg72Pro SNPs are not involved either in susceptibility to developing gliomas or in patient survival, at least in the Brazilian population. 18393224

2008
dbSNP: rs28934575
rs28934575
TP53
0.010 GeneticVariation BEFREE This analysis of H3-G34R mutant fission yeast provides mechanistic insight into how G34R mutation may promote genomic instability in glioma. 28718400

2017
dbSNP: rs78378222
rs78378222
TP53
G 0.720 GeneticVariation GWASCAT Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. 28346443

2017
dbSNP: rs78378222
rs78378222
TP53
G 0.720 GeneticVariation GWASCAT Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. 29743610

2018
dbSNP: rs35850753
rs35850753
TP53
T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies multiple susceptibility loci for glioma. 26424050

2015