Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs113488022
rs113488022
BRAF
0.030 GeneticVariation BEFREE Here we present an unusual case of a patient with TP53-mutated chronic lymphocytic leukemia (CLL) treated with a PI3Kδ inhibitor evolving to clonally related Langerhans cell histiocytosis (LCH) with acquired BRAF V600E and STK11 mutations and loss of expression of PAX-5 and other examined B cell markers. 31317311

2019
dbSNP: rs113488022
rs113488022
BRAF
0.030 GeneticVariation BEFREE We analyzed 121 cases, including 26 HCLs, 52 non-HCL splenic lymphomas, 22 chronic lymphocytic leukemias/small lymphocytic lymphomas (CLLs/SLLs), and 21 plasma cell neoplasms (PCNs) for BRAF V600E expression by IHC. 26071465

2015
dbSNP: rs113488022
rs113488022
BRAF
0.030 GeneticVariation BEFREE Although present at a low frequency, the finding of BRAF V600E has biological and clinical implications for CLL and PLL. 22230299

2012