|
rs183484
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs (NME1 rs3760468, NME2 rs3744660, and RRM1 rs183484) were associated with worse OS in AML patients.
|
29631596 |
2018 |
|
rs3744660
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs (NME1 rs3760468, NME2 rs3744660, and RRM1 rs183484) were associated with worse OS in AML patients.
|
29631596 |
2018 |
|
rs1946518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We determined polymorphisms of NLRP3 (rs35829419), CARD8 (rs2043211), IL-1β (rs16944), IL-18 (rs1946518) and NF-κB -94 ins/del ATTG in de novo AML patients to find out whether they play roles in the susceptibility and severity of AML.
|
27928589 |
2017 |
|
rs2072671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The AC and CC genotypes of rs2072671 (79A>C) were significantly correlated with shorter overall survival rates (P=0.03, hazard ratio=1.84) and first complete remission duration (P=0.007, hazard ratio=3.24) compared with the AA genotype in the NK-AML patients.
|
26354033 |
2015 |
|
rs2072671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The AC and CC genotypes of rs2072671 (79A>C) were significantly correlated with shorter overall survival rates (P=0.03, hazard ratio=1.84) and first complete remission duration (P=0.007, hazard ratio=3.24) compared with the AA genotype in the NK-AML patients.
|
26354033 |
2015 |
|
rs2853669
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We show that rs2853669 CC may be a risk factor for the development of AML that may also be used as a prognostic marker to identify high risk normal karyotype-AML (NK-AML) patients, for treatment guidance.
|
26298771 |
2015 |
|
rs751661633
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The AC and CC genotypes of rs2072671 (79A>C) were significantly correlated with shorter overall survival rates (P=0.03, hazard ratio=1.84) and first complete remission duration (P=0.007, hazard ratio=3.24) compared with the AA genotype in the NK-AML patients.
|
26354033 |
2015 |
|
rs104894230
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia.
|
24480914 |
2014 |
|
rs121913529
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia.
|
24480914 |
2014 |
|
rs1482518887
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia.
|
24480914 |
2014 |
|
rs1799793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
XPD Lys751Gln and not Asp312Asn polymorphism was associated with chemotherapy-induced cardiotoxicity and response to induction chemotherapy in newly diagnosed cytogenetically normal AML patients.
|
24284041 |
2014 |
|
rs2032582
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Impact of ABCB1 single nucleotide polymorphisms 1236C>T and 2677G>T on overall survival in FLT3 wild-type de novo AML patients with normal karyotype.
|
25155901 |
2014 |
|
rs727503094
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia.
|
24480914 |
2014 |
|
rs778036161
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Co-transduction of Kras(G12D) and AML1/ETO induces acute monoblastic leukemia.
|
24480914 |
2014 |
|
rs2304205
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We analyzed two gene variants in IRF3 (rs7251 and rs2304205) on the clinical outcome of 249 AML patients submitted to HLA-identical sibling allo-SCT.
|
23542224 |
2013 |
|
rs11554137
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IDH1 SNP rs11554137 was recently reported in association with poor prognosis in normal karyotype adult acute myeloid leukemia (AML).
|
21873548 |
2011 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the potential involvement of the ABCB1 gene exon 26 3435C>T single nucleotide polymorphism (SNP) in the genetic susceptibility to AML and regulation of P-gp expression and activity in AML cells.
|
17038891 |
2006 |
|
rs1057520026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248).
|
16990784 |
2006 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study we describe the genotyping of the MTHFR C677T polymorphism by melting curve analysis with the LightCycler in a case-controlled study of patients with acute lymphocytic leukemia (ALL), myelogenous leukemia (AML), and chronic myelogenous leukemia (CML), and assess the effect of this common polymorphism on the leukemia risk in adult patients in Turkey.
|
15068389 |
2003 |
|
rs77375493
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The JAK2 V617F mutation is frequently found in ET, while it is rare in de novo AML.
|
29979407 |
2018 |
|
rs13181
|
|
|
0.020 |
GeneticVariation |
BEFREE |
XPD Lys751Gln and not Asp312Asn polymorphism was associated with chemotherapy-induced cardiotoxicity and response to induction chemotherapy in newly diagnosed cytogenetically normal AML patients.
|
24284041 |
2014 |
|
rs77375493
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We applied single nucleotide polymorphism arrays (SNP-A) to study karyotypic abnormalities in patients with atypical myeloproliferative syndromes (MPD), including myeloproliferative/myelodysplastic syndrome overlap both positive and negative for the JAK2 V617F mutation and secondary acute myeloid leukemia (AML).
|
18030353 |
2007 |
|
rs13181
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We hypothesized that XPD Lys751Gln polymorphism may play a role in causation of AML in children and, as shown in adults, may affect the outcome of childhood AML therapy.
|
16150943 |
2006 |
|
rs147001633
|
|
|
0.030 |
GeneticVariation |
BEFREE |
R882H specific DNA hypermethylation events in AML patients were accompanied by R882H specific mis-regulation of several genes with strong cancer connection, which are potential downstream targets of R882H.
|
31620784 |
2019 |
|
rs147001633
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The DNA methyltransferase DNMT3A R882H mutation is observed in 25% of all AML patients.
|
30185810 |
2018 |