rs121913499
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Except for one non-Hodgkin lymphoma (NHL) patient harboring IDH1 mutation p.R132C, all IDH1 and IDH2 missense mutations were observed in patients with AML.
|
20946881 |
2010 |
rs121913499
|
|
C |
0.740 |
CausalMutation |
CLINVAR |
Except for one non-Hodgkin lymphoma (NHL) patient harboring IDH1 mutation p.R132C, all IDH1 and IDH2 missense mutations were observed in patients with AML.
|
20946881 |
2010 |
rs121913499
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Except for one non-Hodgkin lymphoma (NHL) patient harboring IDH1 mutation p.R132C, all IDH1 and IDH2 missense mutations were observed in patients with AML.
|
20946881 |
2010 |
rs121913499
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
rs121913499
|
|
C |
0.740 |
CausalMutation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
rs121913499
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
rs121913499
|
|
|
0.740 |
GeneticVariation |
BEFREE |
IDH1 mutations included R132C (n=4; two post-PMF AML, one post-PV AML and one PMF) and R132S (n=1; post-PMF AML).
|
20410924 |
2010 |
rs121913499
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Impact of genetic features on treatment decisions in AML.
|
22160010 |
2011 |
rs121913499
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Impact of genetic features on treatment decisions in AML.
|
22160010 |
2011 |
rs121913499
|
|
C |
0.740 |
CausalMutation |
CLINVAR |
Impact of genetic features on treatment decisions in AML.
|
22160010 |
2011 |
rs121913499
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.
|
22397365 |
2012 |
rs121913499
|
|
C |
0.740 |
CausalMutation |
CLINVAR |
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.
|
22397365 |
2012 |
rs121913499
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
|
22417203 |
2012 |
rs121913499
|
|
C |
0.740 |
CausalMutation |
CLINVAR |
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
|
22417203 |
2012 |
rs121913499
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
|
22417203 |
2012 |
rs121913499
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
Recurring mutations found by sequencing an acute myeloid leukemia genome.
|
19657110 |
2009 |
rs121913499
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
Recurring mutations found by sequencing an acute myeloid leukemia genome.
|
19657110 |
2009 |
rs121913499
|
|
|
0.740 |
GeneticVariation |
BEFREE |
The frequency of IDH1/2 mutations was 56%, and the IDH1 R132C mutation, which is not common in diffuse gliomas or AML, accounted for 40% of these mutations.
|
22323113 |
2012 |
rs121913499
|
|
|
0.740 |
GeneticVariation |
BEFREE |
The IDH1 R132C mutation commonly found in AML reduces the affinity for isocitrate, and increases the affinity for NADPH and alpha-KG.
|
20142433 |
2010 |
rs121913499
|
|
C |
0.740 |
CausalMutation |
CLINVAR |
The role of mutations in epigenetic regulators in myeloid malignancies.
|
22898539 |
2012 |
rs121913499
|
|
T |
0.740 |
CausalMutation |
CLINVAR |
The role of mutations in epigenetic regulators in myeloid malignancies.
|
22898539 |
2012 |
rs121913499
|
|
A |
0.740 |
CausalMutation |
CLINVAR |
The role of mutations in epigenetic regulators in myeloid malignancies.
|
22898539 |
2012 |