Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
0.030 GeneticVariation BEFREE Although rs1051730 and rs6495309 were shown to be independent risk factors for COPD, validation studies should be performed. 25051068

2014
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
0.030 GeneticVariation BEFREE The data show a statistical association and suggest biological plausibility that the rs6495309T>C polymorphism contributed to increased risks and poor prognosis of both COPD and lung cancer. 23056235

2012
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
0.030 GeneticVariation BEFREE The CHRNA3 rs6495309C > T polymorphism on chromosome 15q25 is associated with the risk of COPD in a Korean population. 23255854

2012
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
0.030 GeneticVariation BEFREE Two SNPs (rs6495309 and rs1051730) located in nicotinic acetylcholine receptor alpha 3 (CHRNA3) gene were genotyped in 1511 patients with COPD, 1559 lung cancer cases and 1677 controls in southern and eastern Chinese populations. 23056235

2012
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
0.030 GeneticVariation BEFREE The rs6495309 CT or TT genotype was associated with a significantly decreased risk of COPD when compared to the rs6495309 CC genotype (adjusted odds ratio = 0.69, 95% confidence interval = 0.50-0.95, P = 0.023). 23255854

2012