rs1800625
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1800625 SNP may be associated with the development of diabetic retinopathy, cancer, and lupus but may be protective against cardiovascular risk.
|
30863465 |
2019 |
rs3810936
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings indicate that gene polymorphisms (rs3810936, rs7848647) of TL1A might correlate with lupus.
|
31081141 |
2019 |
rs7848647
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings indicate that gene polymorphisms (rs3810936, rs7848647) of TL1A might correlate with lupus.
|
31081141 |
2019 |
rs1050501
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Lupus-Associated Fcγ Receptor IIb-I232T Polymorphism Results in Impairment in the Negative Selection of Low-Affinity Germinal Center B Cells Via c-Abl in Mice.
|
29774664 |
2018 |
rs1130864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four of the polymorphisms showed differences between patients and controls. rs3093061 polymorphism was associated with a lower risk of developing lupus principally in the codominant 2 (OR = 0.219, 95% CI 0.108-0.785, P = 0.015) model. rs1130864 was associated with decreased risk mainly under codominant 1 (OR = 0.288, 95% CI 0.143-0.581, P = 0.001) model. rs1205 was associated under the over-dominant model (OR = 0.504, 95% CI 0.270-0.942, P = 0.032).
|
29556849 |
2018 |
rs11889341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Consistent with expression quantitative trait locus (eQTL) analysis, the l</span>upus risk allele of rs11889341 decreased the activity of this putative repressor.
|
29912393 |
2018 |
rs1205
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four of the polymorphisms showed differences between patients and controls. rs3093061 polymorphism was associated with a lower risk of developing lupus principally in the codominant 2 (OR = 0.219, 95% CI 0.108-0.785, P = 0.015) model. rs1130864 was associated with decreased risk mainly under codominant 1 (OR = 0.288, 95% CI 0.143-0.581, P = 0.001) model. rs1205 was associated under the over-dominant model (OR = 0.504, 95% CI 0.270-0.942, P = 0.032).
|
29556849 |
2018 |
rs12583006
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the presence of the AA genotype of the rs12583006 BAFF gene variant increased susceptibility for both lupus and lupus related plaque formation (ORs [95%CI]: 2.8 [1.1-7.1], and 4.4 [1.3-15.4] in the codominant model, respectively).
|
29859654 |
2018 |
rs1518110
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meanwhile, significant difference in genotype frequency at rs1518110 and rs1518111 were found in patients with and without lupus headache (P=0.025, P=0.038, respectively).
|
29199038 |
2018 |
rs1518111
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meanwhile, significant difference in genotype frequency at rs1518110 and rs1518111 were found in patients with and without lupus headache (P=0.025, P=0.038, respectively).
|
29199038 |
2018 |
rs2004640
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although we could not demonstrate susceptibility toward lupus in the presence of IRF5 rs2004640 (G/T) polymorphism, further exploration of the genetic variability of IRF5 may help uncover its pathogenic role in Indian SLE patients.
|
30168487 |
2018 |
rs3093061
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four of the polymorphisms showed differences between patients and controls. rs3093061 polymorphism was associated with a lower risk of developing lupus principally in the codominant 2 (OR = 0.219, 95% CI 0.108-0.785, P = 0.015) model. rs1130864 was associated with decreased risk mainly under codominant 1 (OR = 0.288, 95% CI 0.143-0.581, P = 0.001) model. rs1205 was associated under the over-dominant model (OR = 0.504, 95% CI 0.270-0.942, P = 0.032).
|
29556849 |
2018 |
rs1876453
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These data suggest that rs1876453 in CR2 has long-range effects on gene regulation that decrease susceptibility to lupus.
|
25180293 |
2016 |
rs2275913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis.
|
26515887 |
2016 |
rs2397084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis.
|
26515887 |
2016 |
rs763780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis.
|
26515887 |
2016 |
rs10488631
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2RA rs2104286 and KIF5A rs1678542) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility.
|
26092158 |
2015 |
rs121908117
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, dysfunctional dsDNA degradation by TREX1 D18N induces disease in mice that recapitulates many characteristics of human lupus.
|
25848017 |
2015 |
rs1341239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This preliminary study examined the relevance of a -1149G/T functional single-nucleotide polymorphism (SNP) (rs1341239) in the promoter of the extrapituitary prolactin gene in a cohort of African American and European American women with lupus.
|
26583155 |
2015 |
rs1678542
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2RA rs2104286 and KIF5A rs1678542) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility.
|
26092158 |
2015 |
rs1980422
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2RA rs2104286 and KIF5A rs1678542) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility.
|
26092158 |
2015 |
rs2104286
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2RA rs2104286 and KIF5A rs1678542) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility.
|
26092158 |
2015 |
rs2736340
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2RA rs2104286 and KIF5A rs1678542) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility.
|
26092158 |
2015 |
rs292001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C1q rs292001 polymorphism and C1q antibodies in juvenile lupus and their relation to lupus nephritis.
|
26095468 |
2015 |
rs5029939
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2RA rs2104286 and KIF5A rs1678542) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility.
|
26092158 |
2015 |