rs707824
|
|
T |
0.810 |
GeneticVariation |
GWASCAT |
A SNP in a novel non-HLA region on 6p23 (rs707824, P(NHL) = 5.72×10(-7)) was suggestive of an association conferring susceptibility to lymphoma.
|
23349640 |
2013 |
rs707824
|
|
|
0.810 |
GeneticVariation |
BEFREE |
A SNP in a novel non-HLA region on 6p23 (rs707824, P(NHL) = 5.72×10(-7)) was suggestive of an association conferring susceptibility to lymphoma.
|
23349640 |
2013 |
rs707824
|
|
T |
0.810 |
GeneticVariation |
GWASDB |
A SNP in a novel non-HLA region on 6p23 (rs707824, P(NHL) = 5.72×10(-7)) was suggestive of an association conferring susceptibility to lymphoma.
|
23349640 |
2013 |
rs12289961
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs12289961
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs2621416
|
|
G |
0.800 |
GeneticVariation |
GWASDB |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs2621416
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs2647045
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs2647045
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs4530903
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs4530903
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs6773854
|
|
C |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population.
|
23749188 |
2013 |
rs6773854
|
|
C |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population.
|
23749188 |
2013 |
rs9268853
|
|
C |
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs9268853
|
|
C |
0.800 |
GeneticVariation |
GWASDB |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs948562
|
|
G |
0.800 |
GeneticVariation |
GWASDB |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs948562
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.
|
23349640 |
2013 |
rs11540652
|
|
|
0.720 |
GeneticVariation |
BEFREE |
We previously showed that the HSP90 inhibitor ganetespib potently suppresses T-lymphoma initiation and progression and extends overall survival (OS) in hotspot knockin mice expressing the p53 gain-of-function mutants R175H and R248Q (mutp53) by 30-59%.
|
28300840 |
2017 |
rs267601394
|
|
|
0.720 |
GeneticVariation |
BEFREE |
These results suggest that Ezh2(Y641F) induces lymphoma and melanoma through a vast reorganization of chromatin structure, inducing both repression and activation of polycomb-regulated loci.
|
27135738 |
2016 |
rs267601394
|
|
A |
0.720 |
GeneticVariation |
CLINVAR |
Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma.
|
24563539 |
2014 |
rs267601394
|
|
|
0.720 |
GeneticVariation |
BEFREE |
As EZH2 mutations often coincide with other mutations in lymphoma, we combined the expression of EZH2(Y641F) by crossing these transgenic mice with Eµ-Myc transgenic mice.
|
24802772 |
2014 |
rs11540652
|
|
|
0.720 |
GeneticVariation |
BEFREE |
This was associated with a twofold higher T-lymphoma proliferation in R248Q/- mice compared with G245S/- and null mice.
|
23538418 |
2013 |
rs267601394
|
|
G |
0.720 |
GeneticVariation |
CLINVAR |
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
|
23023262 |
2012 |
rs267601394
|
|
A |
0.720 |
GeneticVariation |
CLINVAR |
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
|
23023262 |
2012 |
rs11540652
|
|
T |
0.720 |
GeneticVariation |
CLINVAR |
|
|
|