Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4986790
rs4986790
TLR4
0.030 GeneticVariation BEFREE The allele frequency of the Asp299Gly polymorphism was 5.9% among 879 blood donors, 6.5% among 1047 patients with microbiologically proven meningococcal disease, and 4.1% among 86 patients who died of meningococcal disease. 11494169

2001
dbSNP: rs121964921
rs121964921
C7
0.010 GeneticVariation BEFREE The missense mutation G357R would make an interesting topic of analysis with regard to meningococcal disease susceptibility in the Spanish population. 12869030

2003
dbSNP: rs1265538677
rs1265538677
CPB2 ; CPB2-AS1
0.010 GeneticVariation BEFREE Therefore, we studied the prevalence of the Thr325Ile dimorphism in the TAFI gene, which is associated with increased TAFIa stability and activity in 50 patients who survived meningococcal disease, in 176 first-degree relatives of a consecutive patient series with meningococcal disease and 212 controls from the same geographic region. 14717966

2004
dbSNP: rs4986790
rs4986790
TLR4
0.030 GeneticVariation BEFREE We investigated an association between 2 TLR4 mutations (Asp(299)Gly and Thr(399)Ile) and meningococcal disease in 197 patients and 214 healthy controls by allele-specific real time polymerase chain reaction and direct sequencing. 16395111

2006
dbSNP: rs4986791
rs4986791
TLR4
0.010 GeneticVariation BEFREE We investigated an association between 2 TLR4 mutations (Asp(299)Gly and Thr(399)Ile) and meningococcal disease in 197 patients and 214 healthy controls by allele-specific real time polymerase chain reaction and direct sequencing. 16395111

2006
dbSNP: rs1965708
rs1965708
SFTPA2
0.010 GeneticVariation BEFREE Gene polymorphism resulting in the substitution of glutamine with lysine at residue 223 in the carbohydrate recognition domain of SP-A2 increases susceptibility to meningococcal disease, as well as the risk of death. 17083016

2006
dbSNP: rs397728201
rs397728201
SFTPA1
0.010 GeneticVariation BEFREE Gene polymorphism resulting in the substitution of glutamine with lysine at residue 223 in the carbohydrate recognition domain of SP-A2 increases susceptibility to meningococcal disease, as well as the risk of death. 17083016

2006
dbSNP: rs4986790
rs4986790
TLR4
0.030 GeneticVariation BEFREE We could not observe a significant influence of CD14 C-159T and TLR4 Asp299Gly polymorphisms on the risk of developing IMD in surviving meningococcal disease patients. 19809507

2009
dbSNP: rs426736
rs426736
CFHR3
0.800 GeneticVariation GWASCAT Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs426736
rs426736
CFHR3
0.800 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs10749071
rs10749071 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs10838427
rs10838427
PRDM11
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs11728925
rs11728925 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs1299491
rs1299491
NUP62 ; IL4I1
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs13070790
rs13070790
ALCAM
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs1749824
rs1749824
ZMIZ1
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs1792624
rs1792624 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs2244614
rs2244614
CES1
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs2406176
rs2406176
TMPRSS15
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs2420864
rs2420864
CNTNAP5
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs4556879
rs4556879
FBXO15
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs4809944
rs4809944 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs4897668
rs4897668 		0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs4972431
rs4972431
OLA1
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010
dbSNP: rs4976846
rs4976846
MYO16 ; MYO16-AS1
0.700 GeneticVariation GWASDB Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. 20694013

2010