Gene: STK11 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057517830
rs1057517830
STK11
A 0.700 CausalMutation CLINVAR

dbSNP: rs1131690920
rs1131690920
STK11
A 0.700 CausalMutation CLINVAR

dbSNP: rs1131690935
rs1131690935
STK11
A 0.700 GeneticVariation CLINVAR Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families. 10408777

1999
dbSNP: rs1131690935
rs1131690935
STK11
A 0.700 GeneticVariation CLINVAR Morphology-dependent resonances in a large dielectric sphere: An asymptotic calculation using local coordinates. 9908348

1992
dbSNP: rs1131690935
rs1131690935
STK11
A 0.700 GeneticVariation CLINVAR Novel mutations in the STK11 gene in Thai patients with Peutz-Jeghers syndrome. 19908348

2009
dbSNP: rs1131690935
rs1131690935
STK11
A 0.700 GeneticVariation CLINVAR Cancer risk associated with STK11/LKB1 germline mutations in Peutz-Jeghers syndrome patients: results of an Italian multicenter study. 23415580

2013
dbSNP: rs1131690935
rs1131690935
STK11
A 0.700 GeneticVariation CLINVAR STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome. 24652667

2014
dbSNP: rs1131690935
rs1131690935
STK11
A 0.700 GeneticVariation CLINVAR Predicting the functional effect of amino acid substitutions and indels. 23056405

2012
dbSNP: rs1131690935
rs1131690935
STK11
A 0.700 GeneticVariation CLINVAR SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. 18687677

2008
dbSNP: rs1131690936
rs1131690936
STK11
A 0.700 CausalMutation CLINVAR

dbSNP: rs1131690947
rs1131690947
STK11
A 0.700 CausalMutation CLINVAR High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients. 21118512

2010
dbSNP: rs1131690950
rs1131690950
STK11
A 0.700 CausalMutation CLINVAR Clinical characteristics and STK11 gene mutations in Chinese children with Peutz-Jeghers syndrome. 26607058

2015
dbSNP: rs1131690950
rs1131690950
STK11
A 0.700 CausalMutation CLINVAR An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus. 17026623

2006
dbSNP: rs1131690950
rs1131690950
STK11
A 0.700 CausalMutation CLINVAR High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome. 16287113

2005
dbSNP: rs1131690950
rs1131690950
STK11
A 0.700 CausalMutation CLINVAR Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. 16707622

2006
dbSNP: rs1131690950
rs1131690950
STK11
A 0.700 CausalMutation CLINVAR Mutation analysis of the STK11/LKB1 gene and clinical characteristics of an Australian series of Peutz-Jeghers syndrome patients. 12372054

2002
dbSNP: rs1131690950
rs1131690950
STK11
A 0.700 CausalMutation CLINVAR Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma. 11389158

2001
dbSNP: rs1131690953
rs1131690953
STK11
A 0.700 GeneticVariation CLINVAR

dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus. 17026623

2006
dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps. 23399955

2013
dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families. 10408777

1999
dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR Exonic STK11 deletions are not a rare cause of Peutz-Jeghers syndrome. 16582077

2006
dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR STK11 genotyping and cancer risk in Peutz-Jeghers syndrome. 15863673

2005
dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome. 12865922

2003
dbSNP: rs121913315
rs121913315
STK11
A 0.700 GeneticVariation CLINVAR High Resolution Melting analysis as a rapid and efficient method of screening for small mutations in the STK11 gene in patients with Peutz-Jeghers syndrome. 23718779

2013