| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
T | 0.700 | CausalMutation | CLINVAR | Germline mutation prevalence in individuals with pancreatic cancer and a history of previous malignancy. | 29360161 | 2018 |
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|
T | 0.700 | CausalMutation | CLINVAR | Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results. | 28008555 | 2017 |
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|
T | 0.700 | CausalMutation | CLINVAR | The importance of proper bioinformatics analysis and clinical interpretation of tumor genomic profiling: a case study of undifferentiated sarcoma and a constitutional pathogenic BRCA2 mutation and an MLH1 variant of uncertain significance. | 25712765 | 2015 |
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|
T | 0.700 | CausalMutation | CLINVAR | Development and validation of a new algorithm for the reclassification of genetic variants identified in the BRCA1 and BRCA2 genes. | 25085752 | 2014 |
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|
T | 0.700 | CausalMutation | CLINVAR | Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis. | 20736950 | 2010 |
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|
T | 0.700 | CausalMutation | CLINVAR | Founder BRCA1/2 mutations in the Europe: implications for hereditary breast-ovarian cancer prevention and control. | 23199084 | 2010 |
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|
T | 0.700 | CausalMutation | CLINVAR | BRCA1/2 mutation analysis in male breast cancer families from North West England. | 17636422 | 2008 |
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|
T | 0.700 | CausalMutation | CLINVAR | Haplotype and cancer risk analysis of two common mutations, BRCA1 4184del4 and BRCA2 2157delG, in high risk northwest England breast/ovarian families. | 14757871 | 2004 |
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|
T | 0.700 | CausalMutation | CLINVAR | Novel BRCA2 mutation in a Polish family with hamartoma and two male breast cancers. | 12114492 | 2002 |
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|
T | 0.700 | CausalMutation | CLINVAR | 2157delG: a frequent mutation in BRCA2 missed by PTT. | 11106360 | 2000 |
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|
T | 0.700 | CausalMutation | CLINVAR | Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene. | 8988179 | 1997 |