Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women. 27836010

2016
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Increased risk of male cancer and identification of a potential prostate cancer cluster region in BRCA2. 26360800

2016
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR The prevalence and spectrum of BRCA1 and BRCA2 mutations in Korean population: recent update of the Korean Hereditary Breast Cancer (KOHBRA) study. 25863477

2015
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR The prevalence and spectrum of BRCA1 and BRCA2 mutations in Korean population: recent update of the Korean Hereditary Breast Cancer (KOHBRA) study. 25863477

2015
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Clinical characteristics of ovarian cancer classified by BRCA1, BRCA2, and RAD51C status. 24504028

2014
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. 23569316

2013
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Nonequivalent gene expression and copy number alterations in high-grade serous ovarian cancers with BRCA1 and BRCA2 mutations. 23633455

2013
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Characteristics and spectrum of BRCA1 and BRCA2 mutations in 3,922 Korean patients with breast and ovarian cancer. 22798144

2012
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer. 21324516

2011
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR The occurrence of germline BRCA1 and BRCA2 sequence alterations in Slovenian population. 21232165

2011
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. 22006311

2011
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. 22006311

2011
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR Founder BRCA1/2 mutations in the Europe: implications for hereditary breast-ovarian cancer prevention and control. 23199084

2010
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR A DGGE system for comprehensive mutation screening of BRCA1 and BRCA2: application in a Dutch cancer clinic setting. 16683254

2006
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada. 17148771

2006
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Variation in cancer risks, by mutation position, in BRCA2 mutation carriers. 11170890

2001
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR Detection of BRCA1 and BRCA2 mutations in breast cancer families by a comprehensive two-stage screening procedure. 10699917

2000
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR Screening for BRCA2 mutations in 81 Dutch breast-ovarian cancer families. 10638982

2000
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR Survival in hereditary breast cancer associated with germline mutations of BRCA2. 10550133

1999
dbSNP: rs80359507
rs80359507
BRCA2
CA 0.700 CausalMutation CLINVAR Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. 9585613

1998
dbSNP: rs80359507
rs80359507
BRCA2
C 0.700 CausalMutation CLINVAR Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene. 8988179

1997