Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes. 21343334

2011
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR p53 in head and neck cancer: functional consequences and environmental implications of TP53 mutations. 21159183

2010
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors. 19147582

2009
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR Transcriptional functionality of germ line p53 mutants influences cancer phenotype. 17606709

2007
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. 12826609

2003
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR Familial sarcoma: challenging pedigrees. 14584079

2003
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein. 11793474

2002
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome. 7887414

1995
dbSNP: rs863224451
rs863224451
TP53
T 0.700 GeneticVariation CLINVAR The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation. 8458321

1993