Source: ALL
Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation BEFREE In single locus analysis, FTO rs8050136 CA (p = 0.0001; OR (95% CI) = 2.4 (1.7-3.4) and AA (p = 0.0001; OR (95% CI) = 3.1 (1.9-5.2); FTO rs1421085 TA (p = 0.0001; OR (95% CI) = 2.1 (1.4-3.0) and AA (p = 0.0001; OR (95% CI) = 3.0 (1.8-5.0); FTO rs9939609 TC (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and CC (p = 0.0001; OR (95% CI) = 4.2 (2.5-7.3) along with TG (p = 0.001; OR (95% CI) = 2.1 (1.3-3.2) and GG (p = 0.021; OR (95% CI) = 3.8 (1.2-11.8) genotypes of FTO rs17817449 with GT (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and TT (p = 0.012; OR (95% CI) = 3.3 (1.8-3.6) genotypes of IRX3 rs3751723 were significantly associated with obesity. 26440677

2017

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE Analysis of MC4R rs17782313, POMC rs1042571, APOE-Hha1 and AGRP rs3412352 genetic variants with susceptibility to obesity risk in North Indians. 26226973

2017

dbSNP: rs17817449
rs17817449
FTO
0.900 GeneticVariation BEFREE Risk allele carriers of rs17817449 SNP had somewhat higher values of weight, body mass index, waist and hip circumference, total cholesterol, triglycerides, adiponectin, and fasting glucose.This study revealed the genetic association between rs9939609 SNP of FTO and obesity in a Romanian population, and to the authors' knowledge, this is the first study to investigate this association in a Romanian population. 27196486

2017

dbSNP: rs17817449
rs17817449
FTO
0.900 GeneticVariation BEFREE In single locus analysis, FTO rs8050136 CA (p = 0.0001; OR (95% CI) = 2.4 (1.7-3.4) and AA (p = 0.0001; OR (95% CI) = 3.1 (1.9-5.2); FTO rs1421085 TA (p = 0.0001; OR (95% CI) = 2.1 (1.4-3.0) and AA (p = 0.0001; OR (95% CI) = 3.0 (1.8-5.0); FTO rs9939609 TC (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and CC (p = 0.0001; OR (95% CI) = 4.2 (2.5-7.3) along with TG (p = 0.001; OR (95% CI) = 2.1 (1.3-3.2) and GG (p = 0.021; OR (95% CI) = 3.8 (1.2-11.8) genotypes of FTO rs17817449 with GT (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and TT (p = 0.012; OR (95% CI) = 3.3 (1.8-3.6) genotypes of IRX3 rs3751723 were significantly associated with obesity. 26440677

2017

dbSNP: rs8050136
rs8050136
FTO
0.900 GeneticVariation BEFREE In single locus analysis, FTO rs8050136 CA (p = 0.0001; OR (95% CI) = 2.4 (1.7-3.4) and AA (p = 0.0001; OR (95% CI) = 3.1 (1.9-5.2); FTO rs1421085 TA (p = 0.0001; OR (95% CI) = 2.1 (1.4-3.0) and AA (p = 0.0001; OR (95% CI) = 3.0 (1.8-5.0); FTO rs9939609 TC (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and CC (p = 0.0001; OR (95% CI) = 4.2 (2.5-7.3) along with TG (p = 0.001; OR (95% CI) = 2.1 (1.3-3.2) and GG (p = 0.021; OR (95% CI) = 3.8 (1.2-11.8) genotypes of FTO rs17817449 with GT (p = 0.0001; OR (95% CI) = 2.1 (1.5-3.1) and TT (p = 0.012; OR (95% CI) = 3.3 (1.8-3.6) genotypes of IRX3 rs3751723 were significantly associated with obesity. 26440677

2017

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE Rs9939609 and rs17782313 are associated with PCOS and obesity-related traits and profiles. 26032905

2016

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE The variant rs17782313 is associated with an increased risk of hypertriglyceridemia in obese children and adolescents. 25948074

2016

dbSNP: rs8050136
rs8050136
FTO
0.900 GeneticVariation BEFREE A region in the first intron of the fat mass- and obesity-associated (FTO) gene, encompassing markers rs9939973, rs8050136, and rs9939609, has been consistently associated with obesity and body mass index (BMI) in different populations. 26529281

2016

dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation BEFREE The SNPs rs1421085, rs17817449 and rs8043757 in the first intron of the FTO gene are associated with increasing risk of obesity in Thais. 25542809

2015

dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation BEFREE Association of obesity with rs1421085 and rs9939609 polymorphisms of FTO gene. 25074273

2015

dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation BEFREE We examined whether a commonly carried obesity-risk variant in the FTO gene (rs1421085 single-nucleotide polymorphism) influences adiposity and is associated with changes in brain function in participants within the Baltimore Longitudinal Study of Aging, one of the longest-running longitudinal aging studies in the United States. 24863145

2015

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE Our findings indicated that rs17782313, rs543874, rs2241423 and rs11084753 were associated with the risk for children obesity in China, and interaction of genetic variants with diet behaviors on obesity. 25637721

2015

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE Genetic variants of the FTO gene rs9939609 A/T and the MC4R gene rs17782313 C/T have been associated with obesity. 23849767

2015

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE MC4R rs17782313 was associated with obesity and could confer a certain susceptibility to T2D that could be independent of its pro-obesity effect. 24151814

2015

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE Our aim was to identify whether the obesity-susceptible gene variants (rs9939609, rs9930506, and rs4783819 in fat mass and obesity-associated gene (FTO); rs12970134 and rs17782313 in melanocortin-4 receptor gene (MC4R); and rs7566605, rs13428113, and rs9308762 in insulin-induced gene 2 [INSIG2]) were associated with NAFLD. 24458218

2015

dbSNP: rs17817449
rs17817449
FTO
0.900 GeneticVariation BEFREE The SNPs rs1421085, rs17817449 and rs8043757 in the first intron of the FTO gene are associated with increasing risk of obesity in Thais. 25542809

2015

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE No significant association was observed for obesity-traits and Mc4R variant rs17782313. 23447422

2014

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE MC4R mutations with partial or total loss of function, as well as the variant rs17782313 mapped near MC4R, are positively associated with obesity. 23147118

2014

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE Melanocortin-4 receptor polymorphism rs17782313: association with obesity and eating in the absence of hunger in Chilean children. 24139164

2014

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE We found correlation for two SNPs--rs11642015 and rs62048402 in the fat mass and obesity-associated protein (FTO) with obesity but no association was detected for rs17782313 located in the MC4R locus in these severely obese individuals. 24385306

2014

dbSNP: rs17782313
rs17782313
0.900 GeneticVariation BEFREE Preliminary findings on the influence of FTO rs9939609 and MC4R rs17782313 polymorphisms on resting energy expenditure, leptin and thyrotropin levels in obese non-morbid premenopausal women. 24307561

2014

dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation GWASCAT Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. 23563607

2013

dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation GWASCAT Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity. 23563609

2013

dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation GWASDB Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. 23563607

2013

dbSNP: rs1421085
rs1421085
FTO
0.900 GeneticVariation GWASDB Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity. 23563609

2013