DisGeNET - a database of gene-disease associations

Parkinson Disease, C0030567

Variant: rs28363170 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs28363170

SLC6A3

0.030

GeneticVariation

BEFREE

The aim of this study was to evaluate a possible relationship between DRD2/ANKK1 (rs1800497) and SLC6A3/DAT1 (rs28363170) gene polymorphisms with the response to levodopa (L-DOPA)-therapy in patients with Parkinson's disease (PD).

30353564

2019

dbSNP:

rs28363170

SLC6A3

0.030

GeneticVariation

BEFREE

Additional studies further investigating the rs28363170 and rs393795 polymorphisms with LID in PD are needed to clarify their role in different ethnicities.

30316985

2019

dbSNP:

rs28363170

SLC6A3

0.030

GeneticVariation

BEFREE

Our data suggest that variants rs28363170 and rs3836790 are not associated with sporadic PD in Han Chinese population.

27353511

2016