Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs74163686
rs74163686
LRRK2
0.040 GeneticVariation BEFREE The Parkinson's disease-associated mutation N1437H impairs conformational dynamics in the G domain of LRRK2. 30592623

2019
dbSNP: rs74163686
rs74163686
LRRK2
0.040 GeneticVariation BEFREE We found that the pathogenic LRRK2 PD-associated mutations (N1437H, R1441C/G/H, Y1699C, G2019S) increase phosphorylation of p62 similar to previously reported substrate Rab proteins. 29519959

2018
dbSNP: rs74163686
rs74163686
LRRK2
0.040 GeneticVariation BEFREE First neuropathological description of a patient with Parkinson's disease and LRRK2 p.N1437H mutation. 22154298

2012
dbSNP: rs74163686
rs74163686
LRRK2
0.040 GeneticVariation BEFREE Novel pathogenic LRRK2 p.Asn1437His substitution in familial Parkinson's disease. 20669305

2010