Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs854560
rs854560
PON1
0.060 GeneticVariation BEFREE To examine the PON1-L55M and -Q192R polymorphisms for polycystic ovary syndrome (PCOS) risk in relation with atherosclerosis risk markers. 30900463

2019
dbSNP: rs854560
rs854560
PON1
0.060 GeneticVariation BEFREE PCOS risk was also linked to PON1 L55M polymorphism in the heterozygote model [0.62 (0.39-0.98)] and dominant model [0.63 (0.41-0.96)]. 29546656

2018
dbSNP: rs854560
rs854560
PON1
0.060 GeneticVariation BEFREE PON1 Leu55Met polymorphism was associated with a significantly increased risk of PCOS (OR=1.31; 95%CI, 1.10-1.55). 28145863

2016
dbSNP: rs854560
rs854560
PON1
0.060 GeneticVariation BEFREE Our study showed that L55M, but not Q192R, polymorphism is significantly associated with reduced PCOS susceptibility only in lean women and also impacts glucose metabolism, lipid parameters, and hyperandrogenemia in them. 25956367

2015
dbSNP: rs854560
rs854560
PON1
0.060 GeneticVariation BEFREE The 192Q/R, but not 55L/M, polymorphism in PON1 gene is associated with the risk of PCOS in south-west Chinese women. 22301914

2012
dbSNP: rs854560
rs854560
PON1
0.060 GeneticVariation BEFREE None of the variants of the Leu55Met PON1 polymorphism was associated with more frequent occurrence of PCOS or metabolic disorders, including insulin resistance. 20334584

2010