rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
But, no significant association was detected between any of the polymorphisms investigated and TB, including rs2076530 SNP that was previously found to be associated with sarcoidosis.
|
20176143 |
2010 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Although rs2076530</span> was not associated with sarcoidosis in either African American sample, a three-locus haplotype that included rs2076530 was associated with sarcoidosis across all three study samples.
|
16080124 |
2005 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our data confirms the association of BTNL2 rs2076530 A allele with sarcoidosis susceptibility in a Portuguese population.
|
23017494 |
2012 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The sarcoidosis risk variant rs2076530 in BTNL2 was associated with all OFG (P = 0.013).
|
27306066 |
2016 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We studied the polymorphism of the rs2076530 SNP of BTNL2 gene in 35 patients with sarcoidosis and cancer compared to 340 sarcoidosis without cancer, 271 controls and 32 cancer matched controls.
|
25078641 |
2014 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Host-genotype analysis revealed an association of the rs2076530 (<i>BTNL2</i>) risk allele with a decrease in bacterial burden (p=0.002).Our results indicate Scadding type-dependent microbiota in sarcoidosis BAL samples.<i>Atopobium</i> spp. and <i>Fusobacterium</i> spp. were identified as sarcoidosis-associated bacteria, which may enable new insights into the pathogenesis and treatment of the disease.
|
29242257 |
2017 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Significant differences were not demonstrable for the sarcoidosis associated splice-site variation (rs2076530 pallelic = 0.80) in our WG cohort.
|
16526951 |
2006 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In our study, 11 single nucleotide polymorphisms (rs28362677, rs2076533, rs2076530, rs2076529, rs2294881, rs3763304, rs2076523, rs28362682, rs3806156, rs9268499, rs3763317), including the functional rs2076530 (G > A) of the BTNL2 gene, and HLA-DRB1 and -DQB1 alleles, were genotyped in 237 Japanese patients diagnosed with sarcoidosis and 287 healthy Japanese control subjects.
|
22991420 |
2012 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
As BTNL2 (butyrophilin-like 2) gene polymorphism was found linked with the susceptibility to sarcoidosis, we investigated whether a specific genotype of BTNL2 gene G16071A (or rs2076530) single-nucleotide polymorphism (SNP) would be associated with the risk of sarcoid uveitis in all patient subgroups.
|
30872286 |
2019 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In summary, HLA-DRB1*14, DRB1*12, and BTNL2 haplotype 4--but not rs2076530 A--are associated with non-Löfgren sarcoidosis.
|
17661910 |
2007 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This meta-analysis indicates that BTNL2 rs2076530 polymorphism contributes to the risk of sarcoidosis.
|
25849037 |
2015 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In the logistic regression models evaluating the association between HLA alleles and chronic sarcoidosis adjusted for rs1049550 and rs2076530, only DRB1*03 was significantly associated with disease resolution.
|
27662826 |
2018 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
An association has been reported between sarcoidosis and a single nucleotide polymorphism in BTNL2, rs2076530, also termed the A allele.
|
21410903 |
2011 |
rs2076530
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Recent studies in sarcoidosis have identified association of a single nucleotide polymorphism (SNP) rs2076530 within BTNL2, a potential T-cell inhibitor, independent of the known DRB1 association.
|
16984233 |
2006 |
rs479777
|
|
|
0.810 |
GeneticVariation |
BEFREE |
We identified chromosome 11q13.1 (rs479777) as a novel locus influencing susceptibility to sarcoidosis with genome-wide significance.
|
22837380 |
2012 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
A common nonsynonymous SNP (rs1049550, C > T, [corrected] R230C) was found to be strongly associated with sarcoidosis.
|
19165924 |
2008 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
Annexin A11 gene polymorphism (R230C variant) and sarcoidosis in a Portuguese population.
|
24032725 |
2013 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In block 2 (rs1049550-rs2573351), the T-C haplotype occurred significantly less frequently (p=0.001), whereas the C-C haplotypes occurred more frequently (p=0.0001) in patients with sarcoidosis than controls.
|
25056970 |
2014 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We also identified a significant SNP-SNP interaction between rs1049550 and a sarcoidosis risk SNP (rs9268839) near the HLA-DRA locus.
|
23151485 |
2013 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
''C'' allele of SNP rs1049550 may be a risk factor for sarcoidosis in overall population.
|
27537711 |
2016 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In this population of Caucasian patients with sarcoidosis, only DRB1*03 was associated with disease resolution after 2 years' follow-up, with no significant interactions found for susceptibility gene SNPs ANXA11 rs1049550 or BTNL2 rs2076530.
|
27662826 |
2018 |
rs1049550
|
|
|
0.770 |
GeneticVariation |
BEFREE |
In line with the previous observation, ANXA11 mRNA expression was not deregulated in sarcoidosis</span> and was independent from rs1049550 variant.
|
21562576 |
2011 |
rs2789679
|
|
|
0.720 |
GeneticVariation |
BEFREE |
The rs2789679 A allele (p=0.00004, OR=1.42, 95% CI 1.17 to 1.73) and rs2819941 T allele (p=0.0006, OR=1.41, 95% CI 1.16 to 1.71) were significantly more frequent in patients with sarcoidosis compared with controls.
|
25056970 |
2014 |
rs2789679
|
|
|
0.720 |
GeneticVariation |
BEFREE |
The meta-analysis revealed that ''T'' allele of ANXA11 SNP rs2573346 and rs2789679 conferred protection against sarcoidosis.
|
27537711 |
2016 |
rs2573346
|
|
|
0.710 |
GeneticVariation |
BEFREE |
The meta-analysis revealed that ''T'' allele of ANXA11 SNP rs2573346 and rs2789679 conferred protection against sarcoidosis.
|
27537711 |
2016 |