| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | BEFREE | Meta-analyses results suggested that DISC1 polymorphisms (rs821616 and rs821597) increased SCZ risk in overall populations. | 29031911 | 2018 |
||||
|
0.080 | GeneticVariation | BEFREE | We found that SNP rs821597 is significantly associated with schizophrenia risk in terms of both allelic and genotypic distribution, while SNP rs821616 is associated with schizophrenia in terms of genotypic distribution, especially in cases above 40 years old. | 30286368 | 2018 |
||||
|
0.080 | GeneticVariation | BEFREE | Moreover, in the male subgroup, the DISC1 rs821597 genotype GA or GA/AA exhibited increased risk of s</span>chizophrenia. | 27236031 | 2016 |
||||
|
0.080 | GeneticVariation | BEFREE | Polymorphisms in DISC1 gene showed only marginally statistically significant association with schizophrenia (rs17817356) or no association whatsoever (rs821597 and rs980989) while two polymorphisms (rs9661837 and rs3737597) were found to be only slightly polymorphic in the samples. | 25889058 | 2015 |
||||
|
0.080 | GeneticVariation | BEFREE | The DISC1 variant rs821597 may confer risk for schizophrenia by its effects on the regional GM in left parahippocampal gyrus and right orbitofrontal cortex with other risk factors for schizophrenia. | 22516458 | 2012 |
||||
|
0.080 | GeneticVariation | BEFREE | Schizophrenia risk-associated polymorphisms [non-synonymous SNPs rs821616 (Cys704Ser) and rs6675281 (Leu607Phe), and rs821597] were associated with the expression of Delta3 and Delta7Delta8. | 19805229 | 2009 |
||||
|
0.080 | GeneticVariation | BEFREE | When haplotypes were constructed with two, three, and four markers, a number of haplotype combinations, especially those including rs821616 and rs821597, were significantly associated with schi</span>zophrenia. | 17286247 | 2007 |
||||
|
0.080 | GeneticVariation | BEFREE | A three-SNP haplotype [hCV219779 (C)-rs821597 (G)-rs821616 (A)] spanning 83 kb of the gene was associated with schizophrenia in a family-based sample (P = 0.002). | 15939883 | 2005 |