|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The rs11833579 was significantly associated with risk of stroke in co-dominant (AA vs. GG: OR (95% CI) = 0.39 (0.23-0.66), adjusted P value = 0.003) and recessive (OR (95% CI) = 0.44 (0.27-0.72), adjusted P value = 0.001) models.
|
31372770 |
2019 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A recent genome-wide association study (GWAS) identified two common polymorphisms (rs12425791 and rs11833579) on chromosome 12p13 that confer risk to stroke, particularly for large artery atherosclerotic (LAA) stroke.
|
26687183 |
2016 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
However, rs11833579 was not associated with increased stroke risk in any genetic model.
|
26312640 |
2016 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggested that the rs12425791 and rs11833579 polymorphisms on Chromosome 12p13 may be associated with the risk of LAA stroke and might be used as candidate biomarkers for LAA stroke susceptibility.
|
26145198 |
2015 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Further, we found no evidence of association of rs11833579 with large artery atherosclerosis (LAA) or small-artery occlusion (SAO) stroke in all genetic models.
|
25096477 |
2014 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
rs12425791 and rs11833579 were not associated with age of stroke onset (P = 0.786 and 0.340, respectively).
|
24995625 |
2014 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent genome-wide association studies (GWAS) have identified two key SNPs (rs11833579 and rs12425791) on chromosome 12p13 that were significantly associated with stroke in Caucasians.
|
22938733 |
2012 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In 2009, a GWAS has confirmed that rs11833579 and rs12425791 near the NINJ2 gene could increase the stroke and ischemic stroke (IS) risk.
|
22795341 |
2012 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This is a precedent study that found genetic variants of rs12425791 and rs11833579 on chromosome 12p13 are independent predictors of stroke-related mortality or stroke recurrence in patients with incident ischemic stroke in Taiwan.
|
22212150 |
2012 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent genome-wide association (GWA) studies have identified two intergenic single nucleotide polymorphisms (SNPs) (rs11833579 and rs12425791) on chromosome 12p13 and within 11 kb of the NINJ2 gene that were significantly associated with stroke in Caucasians.
|
21376321 |
2011 |
|
rs11833579
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent genome-wide association study using four prospective population-based cohorts identified two single-nucleotide polymorphisms (SNPs) on chromosome 12p13, rs12425791 and rs11833579, to be significantly associated with the incidence of atherothrombotic stroke.
|
20448654 |
2010 |