Genotypic analysis demonstrated that there was no significant association between the risk of CHD and stroke and rs3850641 [homozygous comparison (GG vs. AA): OR=1.05, 95% CI=0.74-1.50; heterozygous comparison (GA vs. AA): OR=1.00, 95% CI=0.88-1.13; recessive model (GG vs. GA+AA): OR=1.04, 95% CI=0.76-1.43; dominant model (GG+GA vs. AA): OR=1.01, 95% CI=0.88-1.17].