| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.100 | GeneticVariation | BEFREE | Meta-analysis on the Association Between Norepinephrine Transporter Gene rs2242446, rs5569 Polymorphisms and Risk of Major Depressive Disorder. | 30292339 | 2018 |
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0.100 | GeneticVariation | BEFREE | Association between T-182C, G1287A polymorphism in NET gene and suicidality in major depressive disorder in Chinese patients. | 29703117 | 2018 |
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0.100 | GeneticVariation | BEFREE | Relationship between G1287A of the NET Gene Polymorphisms and Brain Volume in Major Depressive Disorder: A Voxel-Based MRI Study. | 26960194 | 2016 |
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0.100 | GeneticVariation | BEFREE | Different combinations of T-182C and the G1287A polymorphisms of NET gene might increase morbidity risk of M</span>D subpopulations. | 26061302 | 2015 |
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0.100 | GeneticVariation | BEFREE | Association between major depressive disorder and the norepinephrine transporter polymorphisms T-182C and G1287A: a meta-analysis. | 23648227 | 2013 |
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|
0.100 | GeneticVariation | BEFREE | In self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed. | 22727709 | 2012 |
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0.100 | GeneticVariation | BEFREE | The present study suggests that the combined effect of rs2242446 and rs5569 in the NET gene could modify the response to the negative life events in triggering MD. | 18779921 | 2008 |
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0.100 | GeneticVariation | BEFREE | No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population. | 17917281 | 2007 |
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0.100 | GeneticVariation | BEFREE | We analyzed the NET promoter T-182C polymorphism and another silent polymorphism G1287A in exon 9 of the NET gene with a polymerase chain reaction (PCR)-based method in 216 patients with major depression and 210 unrelated, age-and sex-matched healthy control subjects. | 17353941 | 2007 |
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0.100 | GeneticVariation | BEFREE | In a case control association study we investigated the newly identified T-182C polymorphism and an already known G1287A polymorphism in exon 9 of the NET gene in a sample of 193 patients with major depression and 136 healthy, non-related controls. | 11927173 | 2002 |
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0.100 | GeneticVariation | BEFREE | One hundred and five patients with major depression and 74 unrelated matched controls were analyzed for a silent 1287G/A polymorphism (NET-8) in exon 9 of the NET gene. | 10512149 | 1999 |