rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Oncogenic mutation of the p53 gene derived from head and neck cancer prevents cells from undergoing apoptosis after DNA damage.
|
17390010 |
2007 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
P53 germline mutations in childhood cancers and cancer risk for carrier individuals.
|
10864200 |
2000 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Rapid development of post-radiotherapy sarcoma and breast cancer in a patient with a novel germline 'de-novo' TP53 mutation.
|
17572079 |
2007 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Joint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li-Fraumeni syndrome.
|
21305319 |
2011 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
p53 mutants without a functional tetramerisation domain are not oncogenic.
|
10064694 |
1999 |
rs587781525
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
P53 germline mutations in childhood cancers and cancer risk for carrier individuals.
|
10864200 |
2000 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
|
21343334 |
2011 |
rs587781525
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
Germline TP53 mutations is common in patients with two early-onset primary malignancies.
|
25293557 |
2015 |
rs587781525
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis.
|
12826609 |
2003 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations.
|
15925506 |
2005 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Germline TP53 mutations is common in patients with two early-onset primary malignancies.
|
25293557 |
2015 |
rs587781525
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations.
|
15925506 |
2005 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
High frequency of germline TP53 mutations in a prospective adult-onset sarcoma cohort.
|
23894400 |
2013 |
rs587781525
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis.
|
12826609 |
2003 |