Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913530
rs121913530
KRAS
G 0.700 CausalMutation CLINVAR

dbSNP: rs370004591
rs370004591
TTN ; TTN-AS1 ; LOC101927055
0.700 GeneticVariation UNIPROT

dbSNP: rs374711533
rs374711533
DCLK3
0.700 GeneticVariation UNIPROT

dbSNP: rs770167074
rs770167074
BMP2K
0.700 GeneticVariation UNIPROT

dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
0.010 GeneticVariation BEFREE Although our sample size was limited, these results indicate that the Ser326Cys variant may be related to squamous cell lung cancer susceptibility. 10744126

1999
dbSNP: rs876658657
rs876658657
MLH1
0.010 GeneticVariation BEFREE These results suggest that the hMLH1 -93G-->A polymorphism could be used as a marker of genetic susceptibility to squamous cell carcinoma of the lung. 15382050

2004
dbSNP: rs1048943
rs1048943
CYP1A1
0.010 GeneticVariation BEFREE CYP1A1 Ile462Val and MPO G-463A interact to increase risk of adenocarcinoma but not squamous cell carcinoma of the lung. 16195240

2006
dbSNP: rs1057520039
rs1057520039
STK11
G 0.700 GeneticVariation CLINVAR LKB1 modulates lung cancer differentiation and metastasis. 17676035

2007
dbSNP: rs730881972
rs730881972
STK11
T 0.700 GeneticVariation CLINVAR LKB1 modulates lung cancer differentiation and metastasis. 17676035

2007
dbSNP: rs764449808
rs764449808
STK11
G 0.700 GeneticVariation CLINVAR LKB1 modulates lung cancer differentiation and metastasis. 17676035

2007
dbSNP: rs1042522
rs1042522
TP53
0.010 GeneticVariation BEFREE Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. 17059853

2007
dbSNP: rs1057520001
rs1057520001
TP53
0.010 GeneticVariation BEFREE Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. 17059853

2007
dbSNP: rs1131691014
rs1131691014
TP53
0.010 GeneticVariation BEFREE Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. 17059853

2007
dbSNP: rs121913376
rs121913376
BRAF
0.010 GeneticVariation BEFREE In summary, we found a novel B-RAF V470F mutation in lung squamous cell carcinoma that showed response to gefitinib. 17409805

2007
dbSNP: rs1801270
rs1801270
CDKN1A
0.010 GeneticVariation BEFREE Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. 17059853

2007
dbSNP: rs878854066
rs878854066
TP53
0.010 GeneticVariation BEFREE Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. 17059853

2007
dbSNP: rs886039484
rs886039484
TP53
0.010 GeneticVariation BEFREE Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. 17059853

2007
dbSNP: rs121434592
rs121434592
AKT1
0.010 GeneticVariation BEFREE Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung. 18256540

2008
dbSNP: rs6183
rs6183
GHR
0.010 GeneticVariation BEFREE In different histological types of lung cancer, Thr495Pro SNP was significantly associated with small cell and squamous cell lung cancer, but not with adenocarcinoma, which suggested a potential interaction between this polymorphism and metabolic pathways related to smoking. 18299312

2008
dbSNP: rs150036236
rs150036236
EGFR
A 0.700 CausalMutation CLINVAR Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma. 20942962

2010
dbSNP: rs34192549
rs34192549
EPHA2
G 0.700 GeneticVariation CLINVAR EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation. 20360610

2010
dbSNP: rs1057519789
rs1057519789
DDR2
T 0.700 GeneticVariation CLINVAR Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. 22328973

2011
dbSNP: rs1057519790
rs1057519790
DDR2
T 0.700 GeneticVariation CLINVAR Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. 22328973

2011
dbSNP: rs144594252
rs144594252
DDR2
G 0.700 GeneticVariation CLINVAR Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. 22328973

2011
dbSNP: rs376303676
rs376303676
DDR2
T 0.700 GeneticVariation CLINVAR Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. 22328973

2011