Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE The risk observed for A1298C was 2.28 and 2.12 times higher in variants (AC + CC) of both DVT and CAD (OR = 2.28, 95%CI = 1.09-4.75 and OR = 2.12, 95%CI = 1.02-4.40, respectively). 31571711

2020

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Thus, the aim of the present study is to determine the prevalence of FVL, MTHFR C677T and MTHFR A1298C gene polymorphisms in patients with DVT in central Iran. 29855758

2018

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE The presence of homozygous MTHFR A1298C mutation was significantly associated with DVT (P=0.020). 21080081

2011

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Factor V (FV)-Leiden (G16891A)-, factor II(G20210A)-mutations, protein C- and S, as well as methylenetetrahydrofolate reductase (MTHFR) polymorphisms at C677T and A1298C, and serum homocysteine levels (hcy) were determined in 29 patients with SVT and 26 with DVT. 20881312

2011

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Recurrent deep vein thrombosis and pulmonary embolism in a young man with Klinefelter's syndrome and heterozygous mutation of MTHFR-677C>T and 1298A>C. 20449891

2010

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE We therefore compared the prevalence of factor V Leiden, prothrombin G20210A, methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C, and plasminogen activator inhibitor 4G/5G polymorphisms between 50 patients with symptomatic DVT within 3 weeks after elective THA and an asymptomatic control group of 85 patients. 18800213

2009

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Plasma concentration of tHcy in AC genotype of MTHFR A1298C was increased in patients with OAD and in patients with DVT. 18800176

2008

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE The prevalences of the C677T and A1298C genotypes did not differ significantly in 772 individuals with documented coronary artery disease (CAD), 137 individuals with deep-vein thrombosis (DVT), and 329 individuals without documented vascular disease. 11274015

2001

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE These data do not support a critical role of MTHFR 1298 A --> C in the predisposition to DVT. 10233437

1999