Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1131691014
rs1131691014
0.010 GeneticVariation BEFREE In conclusions, p53 Arg72Pro polymorphism is a potential marker of HP infection-related HNSCC rather than a susceptibility gene polymorphism. 24289637

2013

dbSNP: rs878854066
rs878854066
0.010 GeneticVariation BEFREE In conclusions, p53 Arg72Pro polymorphism is a potential marker of HP infection-related HNSCC rather than a susceptibility gene polymorphism. 24289637

2013

dbSNP: rs1051740
rs1051740
0.010 GeneticVariation BEFREE We determined the association between charred meat consumption, cigarette smoking, microsomal epoxide hydrolase (mEH) polymorphisms (rs1051740 and rs2234922), and colorectal adenomas and hyperplastic polyps (HPs) and explored gene-environment interactions. 21598178

2011

dbSNP: rs2234922
rs2234922
0.010 GeneticVariation BEFREE We determined the association between charred meat consumption, cigarette smoking, microsomal epoxide hydrolase (mEH) polymorphisms (rs1051740 and rs2234922), and colorectal adenomas and hyperplastic polyps (HPs) and explored gene-environment interactions. 21598178

2011

dbSNP: rs8042919
rs8042919
0.010 GeneticVariation BEFREE We also found that the common Thr1482Ile polymorphism was associated with an elevated risk of both adenomatous and hyperplastic polyps. 17823441

2007

dbSNP: rs1042821
rs1042821
0.010 GeneticVariation BEFREE In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps. 16771955

2006

dbSNP: rs1799977
rs1799977
0.010 GeneticVariation BEFREE In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps. 16771955

2006

dbSNP: rs536562413
rs536562413
0.010 GeneticVariation BEFREE In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps. 16771955

2006

dbSNP: rs17655
rs17655
0.010 GeneticVariation BEFREE In a Minnesota-based case-control study of cases with only adenomatous polyps (n = 384), only hyperplastic polyps (n = 191), or both types of polyps (n = 119) versus polyp-free controls (n = 601), we investigated the role of polymorphisms in the DNA repair genes O(6)-methylguanine methyltransferase (MGMT; p.L84F and p.I143V), XPD (p.D312N and p.K751Q), and XPG (p.D1104H). 16284370

2005

dbSNP: rs1800470
rs1800470
0.010 GeneticVariation BEFREE Whereas adenoma risk did not vary by TGFbeta1 L10P genotype, these results suggest that the L10P variant allele may have a protective role in the development of colorectal hyperplastic polyps, possibly consistent with its role as an inhibitor of epithelial growths. 15020570

2004

dbSNP: rs1463038513
rs1463038513
APC
0.010 GeneticVariation BEFREE The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps. 10938175

2000

dbSNP: rs1801155
rs1801155
APC
0.010 GeneticVariation BEFREE The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps. 10938175

2000

dbSNP: rs1801166
rs1801166
APC
0.010 GeneticVariation BEFREE Four patients had a germ-line E1317Q missense variant of APC that was not present in controls; one of these individuals had an unusually large number of metaplastic polyps of the colorectum. 9724771

1998