|
rs1042821
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps.
|
16771955 |
2006 |
|
rs1799977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps.
|
16771955 |
2006 |
|
rs536562413
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps.
|
16771955 |
2006 |
|
rs17655
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a Minnesota-based case-control study of cases with only adenomatous polyps (n = 384), only hyperplastic polyps (n = 191), or both types of polyps (n = 119) versus polyp-free controls (n = 601), we investigated the role of polymorphisms in the DNA repair genes O(6)-methylguanine methyltransferase (MGMT; p.L84F and p.I143V), XPD (p.D312N and p.K751Q), and XPG (p.D1104H).
|
16284370 |
2005 |
|
rs1801166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four patients had a germ-line E1317Q missense variant of APC that was not present in controls; one of these individuals had an unusually large number of metaplastic polyps of the colorectum.
|
9724771 |
1998 |
|
rs113488022
|
|
|
0.090 |
GeneticVariation |
BEFREE |
BRAF mutations (V600E) were observed in 45.8% (11 of 24) of HPs, 60.9% (14 of 23) of SSAs, and 63.6% (7 of 11) of SSANs, and were equally found in both SSA and carcinoma/HGD areas of the individual SSANs.
|
21263251 |
2011 |
|
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
BRAF mutations (V600E) were observed in 45.8% (11 of 24) of HPs, 60.9% (14 of 23) of SSAs, and 63.6% (7 of 11) of SSANs, and were equally found in both SSA and carcinoma/HGD areas of the individual SSANs.
|
21263251 |
2011 |
|
rs113488022
|
|
|
0.090 |
GeneticVariation |
BEFREE |
BRAF V600E mutations were seen in 83% of proximal and 74% of distal hyperplastic polyps.
|
19855373 |
2010 |
|
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
BRAF V600E mutations were seen in 83% of proximal and 74% of distal hyperplastic polyps.
|
19855373 |
2010 |
|
rs113488022
|
|
|
0.090 |
GeneticVariation |
BEFREE |
BRAF V600E mutation analysis was performed in 148 selected cases; mutations were found in 44/49 (90%) of lesions diagnosed as sessile serrated adenoma, in 10/34 (29%) of hyperplastic polyps of microvesicular type, in 4/11 (36%) of traditional serrated adenomas, in 10/10 (100%) of mixed hyperplastic adenomatous polyps, and in 2/42 (5%) of "conventional" adenomas.
|
19126563 |
2009 |
|
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
BRAF V600E mutation analysis was performed in 148 selected cases; mutations were found in 44/49 (90%) of lesions diagnosed as sessile serrated adenoma, in 10/34 (29%) of hyperplastic polyps of microvesicular type, in 4/11 (36%) of traditional serrated adenomas, in 10/10 (100%) of mixed hyperplastic adenomatous polyps, and in 2/42 (5%) of "conventional" adenomas.
|
19126563 |
2009 |
|
rs113488022
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Both the HP and TSA exhibited the V600E BRAF mutation without MSI or MMR deficiency.
|
17914558 |
2007 |
|
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Both the HP and TSA exhibited the V600E BRAF mutation without MSI or MMR deficiency.
|
17914558 |
2007 |