rs13428812
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the number of minor alleles of both rs6733868 and rs13428812 was significantly correlated with the risk of <i>Helicobacter pylori</i> (HP) infection (P=0.0070 and P=0.0050, respectively).
|
30867787 |
2019 |
rs1463038513
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps.
|
10938175 |
2000 |
rs17655
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a Minnesota-based case-control study of cases with only adenomatous polyps (n = 384), only hyperplastic polyps (n = 191), or both types of polyps (n = 119) versus polyp-free controls (n = 601), we investigated the role of polymorphisms in the DNA repair genes O(6)-methylguanine methyltransferase (MGMT; p.L84F and p.I143V), XPD (p.D312N and p.K751Q), and XPG (p.D1104H).
|
16284370 |
2005 |
rs1799977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps.
|
16771955 |
2006 |
rs1800470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Whereas adenoma risk did not vary by TGFbeta1 L10P genotype, these results suggest that the L10P variant allele may have a protective role in the development of colorectal hyperplastic polyps, possibly consistent with its role as an inhibitor of epithelial growths.
|
15020570 |
2004 |
rs1801155
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps.
|
10938175 |
2000 |
rs1801166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four patients had a germ-line E1317Q missense variant of APC that was not present in controls; one of these individuals had an unusually large number of metaplastic polyps of the colorectum.
|
9724771 |
1998 |
rs2234922
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We determined the association between charred meat consumption, cigarette smoking, microsomal epoxide hydrolase (mEH) polymorphisms (rs1051740 and rs2234922), and colorectal adenomas and hyperplastic polyps (HPs) and explored gene-environment interactions.
|
21598178 |
2011 |
rs536562413
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a Minnesota-based case-control study of individuals with adenomas (N=401), hyperplastic polyps (N=195), or both adenomas and hyperplastic polyps (N=123) versus polyp-free controls (N=624), we investigated the role of hMLH1-93G>A, hMLH1 I219V, and hMSH6 G39E polymorphisms in increasing the risk of colorectal polyps.
|
16771955 |
2006 |
rs6733868
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the number of minor alleles of both rs6733868 and rs13428812 was significantly correlated with the risk of <i>Helicobacter pylori</i> (HP) infection (P=0.0070 and P=0.0050, respectively).
|
30867787 |
2019 |
rs777980327
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results also provide evidence that--just as BRAF V600E mutations in hyperplastic polyps and benign nevi- a mutated driver gene does not imply malignant behavior per se but may set the basis for malignant transformation.
|
26493284 |
2016 |
rs8042919
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found that the common Thr1482Ile polymorphism was associated with an elevated risk of both adenomatous and hyperplastic polyps.
|
17823441 |
2007 |
rs878854066
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusions, p53 Arg72Pro polymorphism is a potential marker of HP infection-related HNSCC rather than a susceptibility gene polymorphism.
|
24289637 |
2013 |