Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs777980327
rs777980327
APC
0.010 GeneticVariation BEFREE Our results also provide evidence that--just as BRAF V600E mutations in hyperplastic polyps and benign nevi- a mutated driver gene does not imply malignant behavior per se but may set the basis for malignant transformation. 26493284

2016
dbSNP: rs113488022
rs113488022
BRAF
0.090 GeneticVariation BEFREE The BRAF V600E mutation is one of the most frequent molecular abnormalities identified in hyperplastic polyps and sessile serrated adenomas. 26030242

2015
dbSNP: rs121913377
rs121913377
BRAF
0.090 GeneticVariation BEFREE The BRAF V600E mutation is one of the most frequent molecular abnormalities identified in hyperplastic polyps and sessile serrated adenomas. 26030242

2015
dbSNP: rs1463038513
rs1463038513
APC
0.010 GeneticVariation BEFREE The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps. 10938175

2000
dbSNP: rs1801155
rs1801155
APC
0.010 GeneticVariation BEFREE The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps. 10938175

2000
dbSNP: rs113488022
rs113488022
BRAF
0.090 GeneticVariation BEFREE These findings indicate that adenomas might be less important in the cancer development in the group of families with BRAF-V600E mutations and indirectly support a previous hypothesis that tumors might develop through the hyperplastic polyp-serrated adenoma pathway. 17119056

2006
dbSNP: rs121913377
rs121913377
BRAF
0.090 GeneticVariation BEFREE These findings indicate that adenomas might be less important in the cancer development in the group of families with BRAF-V600E mutations and indirectly support a previous hypothesis that tumors might develop through the hyperplastic polyp-serrated adenoma pathway. 17119056

2006
dbSNP: rs8042919
rs8042919
TRPM7
0.010 GeneticVariation BEFREE We also found that the common Thr1482Ile polymorphism was associated with an elevated risk of both adenomatous and hyperplastic polyps. 17823441

2007
dbSNP: rs1051740
rs1051740
EPHX1
0.010 GeneticVariation BEFREE We determined the association between charred meat consumption, cigarette smoking, microsomal epoxide hydrolase (mEH) polymorphisms (rs1051740 and rs2234922), and colorectal adenomas and hyperplastic polyps (HPs) and explored gene-environment interactions. 21598178

2011
dbSNP: rs2234922
rs2234922
EPHX1
0.010 GeneticVariation BEFREE We determined the association between charred meat consumption, cigarette smoking, microsomal epoxide hydrolase (mEH) polymorphisms (rs1051740 and rs2234922), and colorectal adenomas and hyperplastic polyps (HPs) and explored gene-environment interactions. 21598178

2011
dbSNP: rs113488022
rs113488022
BRAF
0.090 GeneticVariation BEFREE We investigated 194 serrated lesions of the colon, comprising 42 sessile serrated adenomas/polyps, 16 traditional serrated adenomas, 136 hyperplastic polyps and 20 tubular/tubulovillous adenomas (conventional adenomas) with the novel BRAF V600E mutation-specific antibody VE1. 23887306

2014
dbSNP: rs121913377
rs121913377
BRAF
0.090 GeneticVariation BEFREE We investigated 194 serrated lesions of the colon, comprising 42 sessile serrated adenomas/polyps, 16 traditional serrated adenomas, 136 hyperplastic polyps and 20 tubular/tubulovillous adenomas (conventional adenomas) with the novel BRAF V600E mutation-specific antibody VE1. 23887306

2014
dbSNP: rs1800470
rs1800470
TGFB1
0.010 GeneticVariation BEFREE Whereas adenoma risk did not vary by TGFbeta1 L10P genotype, these results suggest that the L10P variant allele may have a protective role in the development of colorectal hyperplastic polyps, possibly consistent with its role as an inhibitor of epithelial growths. 15020570

2004