|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
This study indicates that the allele T and genotype CT of MTHFR C677T polymorphism are significantly associated with POAG while allele C and CC genotype may be protective for it.
|
27585654 |
2016 |
|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Ours is the first report demonstrating association of MTHFR C677T with POAG but not PACG in individuals from North India.
|
25054348 |
2014 |
|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
This meta-analysis suggested that there were significant associations between MTHFR C677T polymorphism and POAG in allelic model and additive model for PB subgroup which indicated that the T allele or TT genotype might increase the risk of POAG, whereas no evidence of significant association was shown of the overall studied population.
|
23123730 |
2013 |
|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We found that POAG is associated with elevated plasma tHcy levels, but not serum folic acid, vitamin B(12), vitamin B(6) levels, or MTHFR C677T genotype.
|
22902176 |
2012 |
|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The overall distribution of the C677T genotype was found to be significantly associated with PCAG (CC 69%, CT 21%, TT 10%; p=0.001, chi(2)=12.6), but not with POAG (CC 71%, CT 28%, TT 1%; p=0.98, chi(2)=0.02) as compared to the controls (CC 71%, CT 29%, TT 1%).
|
19936026 |
2009 |
|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The MTHFR C677T polymorphism was found to be associated with PCAG but not POAG in patients of Pakistani origin.
|
18385801 |
2008 |
|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Patients with primary open-angle glaucoma (n = 243) and controls (n = 187) were analyzed for the MTHFR 677 C > T and 1298 A > C polymorphisms using minisequencing technique.
|
17558844 |
2007 |
|
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The MTHFR C677T variant leading to moderate hyperhomocysteinemia may play a role in the pathogenesis of POAG acting as a genetic risk factor.
|
15808177 |
2005 |