|
rs2165241
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A meta-analysis showed that the risk of POAG in individuals carrying the C allele of rs2165241 was 1.26 times higher compared with those carrying the T allele (odds ratio (OR)=1.26, 95% confidence interval (CI): 1.09~1.46) in the total population.
|
25750511 |
2015 |
|
rs2165241
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In a recessive genetic model, the T allele of the rs2165241 polymorphism was significantly associated with the risk of primary open-angle glaucoma (TT vs. CC: odds ratios = 2.19, 95% confidence interval = [1.33-3.62]).
|
24893574 |
2015 |
|
rs2165241
|
|
|
0.070 |
GeneticVariation |
BEFREE |
As for SNP rs2165241, the "T" allele frequency in the POAG patients (0.46) was slightly higher than the frequency in controls (0.39), but this difference was not statistically significant (p = 0.176).
|
21510775 |
2012 |
|
rs2165241
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Allele and genotype frequencies of SNPs rs1048661, rs2165241, and rs3825942 were extracted for analysis in Reviewer Manager: (1) comparison of the allelic distributions between XFS and XFG, (2) allelic association of LOXL1 SNPs with XFS/XFG, (3) associations in homozygote, heterozygote, and dominant and recessive models, and (4) allelic association with primary open angle glaucoma (POAG).
|
20142848 |
2010 |
|
rs2165241
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Individual LOXL1 SNPs, rs1048661, rs3825942, and rs2165241, were not associated with POAG in the Chinese population.
|
19098994 |
2008 |
|
rs2165241
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We evaluated the association of three LOXL1 variants (rs1048661, rs3825942, and rs2165241) in 142 Japanese patients with exfoliation syndrome (EX; n=59) and exfoliation glaucoma (EG; n=83) as well as in 251 control patients aged 70 years or older with primary open-angle glaucoma (PG; n=40), normal tension glaucoma (NG; n=54), and cataract (CT; n=157).
|
18958304 |
2008 |
|
rs2165241
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The three associated SNPs of LOXL1 (rs1048661, rs3825942, and rs2165241) were screened in 208 unrelated and clinically well-characterized glaucoma cases comprising patients with POAG (n = 112) or PACG (n = 96) along with 105 ethnically matched normal control subjects from Indian populations.
|
18223248 |
2008 |