Gene: PCAT1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16901979
rs16901979
PCAT1 ; CASC19
A 0.800 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
G 0.800 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs10086908
rs10086908
PCAT1 ; LOC105375751
T 0.700 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs16901814
rs16901814
PCAT1 ; LOC105375751
G 0.700 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs75777376
rs75777376
PCAT1 ; LOC105375751 ; LOC105375753
C 0.700 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs10505474
rs10505474
POU5F1B ; CASC8 ; PCAT1
0.010 GeneticVariation BEFREE rs10505474 and rs7837328 at 8q24 cumulatively confer risk of prostate cancer in Northern Han Chinese. 24815458

2014
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
0.800 GeneticVariation BEFREE A combined analysis with four additional studies (total: 4,296 cases and 4,299 controls) confirms association with prostate cancer for rs6983267 in the centromeric locus (P = 9.42 x 10(-13); heterozygote odds ratio (OR): 1.26, 95% confidence interval (c.i.): 1.13-1.41; homozygote OR: 1.58, 95% c.i.: 1.40-1.78). 17401363

2007
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
G 0.800 GeneticVariation GWASCAT A combined analysis with four additional studies (total: 4,296 cases and 4,299 controls) confirms association with prostate cancer for rs6983267 in the centromeric locus (P = 9.42 x 10(-13); heterozygote odds ratio (OR): 1.26, 95% confidence interval (c.i.): 1.13-1.41; homozygote OR: 1.58, 95% c.i.: 1.40-1.78). 17401363

2007
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
0.800 GeneticVariation BEFREE A highly significant association (odds ratio=2.84 and p-value=0.002) was found between rs6983267 and prostate cancer in the Greek population. 22070222

2011
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
G 0.800 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs6983561
rs6983561
PCAT1 ; CASC19
C 0.780 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs116041037
rs116041037
PCAT1 ; CASC19
A 0.710 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs10086908
rs10086908
PCAT1 ; LOC105375751
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs16902104
rs16902104
POU5F1B ; CASC8 ; PCAT1 ; CASC21
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs72725879
rs72725879
PCAT1 ; PRNCR1 ; CASC19
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs77541621
rs77541621
PCAT1
A 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs16901979
rs16901979
PCAT1 ; CASC19
0.800 GeneticVariation BEFREE A meta-analysis across 10 studies including our results of four 8q24 variants (rs1442295 and DG8S737-region 1, rs16901979-region 2, and rs6983267-region 3) and prostate cancer risk demonstrated strong associations across a wide array of study designs and populations. 18231127

2008
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
0.800 GeneticVariation BEFREE A meta-analysis across 10 studies including our results of four 8q24 variants (rs1442295 and DG8S737-region 1, rs16901979-region 2, and rs6983267-region 3) and prostate cancer risk demonstrated strong associations across a wide array of study designs and populations. 18231127

2008
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
0.800 GeneticVariation BEFREE A single nucleotide polymorphism (SNP) rs6983267, located within the 8q24 region, is strongly associated with risk of colorectal and prostate cancer. 19895682

2009
dbSNP: rs16902094
rs16902094
CASC8 ; PCAT1 ; CASC21
0.720 GeneticVariation BEFREE A statistically significant interaction was observed for each of 2 SNPs in the 8q24 region (rs620861 and rs16902094), 25(OH)D concentration, and fatal prostate cancer on both multiplicative and additive scales (P ≤ 0.001). 28399564

2017
dbSNP: rs188140481
rs188140481
PCAT1 ; CASC19
A 0.720 GeneticVariation GWASCAT A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer. 23104005

2012
dbSNP: rs6983267
rs6983267
POU5F1B ; CASC8 ; PCAT1 ; CCAT2
0.800 GeneticVariation BEFREE Analysis of the National Cancer Institute's Cancer Genetic Markers of Susceptibility (CGEMS) prostate cancer association study database alone and in combination with our data provided further evidence for this second prostate cancer risk locus; in the combined analysis, the allele frequencies for rs6983267 differed statistically significantly between case patients and control subjects (P = 1.61 x 10(-9)). 17925536

2007
dbSNP: rs183373024
rs183373024
PCAT1 ; PRNCR1 ; CASC19
G 0.700 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016

2018
dbSNP: rs1902432
rs1902432
PCAT1 ; LOC105375751
0.010 GeneticVariation BEFREE Besides, rs1902432 in <i>PCAT1</i> was significantly associated with increased risk of PCa (Additive model: OR = 1.19, <i>P</i> = 0.014; Co-dominant model: CC <i>vs.</i> TT, OR = 1.45, <i>P</i> =0.012; Recessive model: CC <i>vs.</i> TT/CT, OR= 1.34, <i>P</i> = 0.027). 29721051

2018