Gene: BRCA1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs41293459
rs41293459
BRCA1
T 0.700 CausalMutation CLINVAR Trans-activation-based risk assessment of BRCA1 BRCT variants with unknown clinical significance. 30458859

2018
dbSNP: rs41293459
rs41293459
BRCA1
T 0.700 CausalMutation CLINVAR The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium. 28490613

2018
dbSNP: rs45553935
rs45553935
BRCA1
G 0.700 CausalMutation CLINVAR Mechanism for survival of homozygous nonsense mutations in the tumor suppressor gene BRCA1. 29712865

2018
dbSNP: rs45553935
rs45553935
BRCA1
G 0.700 CausalMutation CLINVAR Subsequent breast and high grade serous carcinomas after risk-reducing salpingo-oophorectomy in BRCA mutation carriers and patients with history of breast cancer. 30055521

2018
dbSNP: rs762635795
rs762635795
BRCA1
T 0.700 CausalMutation CLINVAR Screening of over 1000 Indian patients with breast and/or ovarian cancer with a multi-gene panel: prevalence of BRCA1/2 and non-BRCA mutations. 29470806

2018
dbSNP: rs80356857
rs80356857
BRCA1
T 0.700 CausalMutation CLINVAR The germline mutational landscape of BRCA1 and BRCA2 in Brazil. 29907814

2018
dbSNP: rs80356862
rs80356862
BRCA1
C 0.700 GeneticVariation CLINVAR Description of Genetic Variants in BRCA Genes in Mexican Patients with Ovarian Cancer: A First Step towards Implementing Personalized Medicine. 29997359

2018
dbSNP: rs80356862
rs80356862
BRCA1
C 0.700 GeneticVariation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80356862
rs80356862
BRCA1
C 0.700 GeneticVariation CLINVAR Validation and Implementation of BRCA1/2 Variant Screening in Ovarian Tumor Tissue. 29936257

2018
dbSNP: rs80356959
rs80356959
BRCA1
G 0.700 CausalMutation CLINVAR Dealing With BRCA1/2 Unclassified Variants in a Cancer Genetics Clinic: Does Cosegregation Analysis Help? 30254663

2018
dbSNP: rs80357063
rs80357063
BRCA1
C 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357150
rs80357150
BRCA1
T 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357239
rs80357239
BRCA1
T 0.700 CausalMutation CLINVAR BRCA germline mutations in an unselected nationwide cohort of Chinese patients with ovarian cancer and healthy controls. 30078507

2018
dbSNP: rs80357254
rs80357254
BRCA1
A 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357385
rs80357385
BRCA1
A 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357418
rs80357418
BRCA1
T 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357461
rs80357461
BRCA1
A 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357516
rs80357516
BRCA1
TACTA 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357580
rs80357580
BRCA1
ATTAG 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357785
rs80357785
BRCA1
GA 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357841
rs80357841
BRCA1
TA 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80357914
rs80357914
BRCA1 ; NBR2
ACT 0.700 CausalMutation CLINVAR Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer Susceptibility. 30262796

2018
dbSNP: rs80357944
rs80357944
BRCA1
T 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80358087
rs80358087
BRCA1
G 0.700 GeneticVariation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018
dbSNP: rs80358087
rs80358087
BRCA1
A 0.700 CausalMutation CLINVAR Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. 29446198

2018