Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.090 | GeneticVariation | BEFREE | However, the <i>MTHFR</i> A1298C polymorphism may be associated with the decreasing risk of lung cancer. | 30323671 | 2018 |
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0.090 | GeneticVariation | BEFREE | However, no significant association between the MTHFR A1298C polymorphism and lung cancer risk was found in either the Caucasian or Asian group with any genetic models. | 27173216 | 2016 |
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0.090 | GeneticVariation | BEFREE | The association between MTHFR C677T and A1298C genotype and haplotype frequencies in risk for lung cancer (LC) was investigated in the Jordanian population. | 25921104 | 2015 |
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0.090 | GeneticVariation | BEFREE | Our meta-analysis supports that the common polymorphisms of C677T and A1298C </span>in MTHFR gene are not susceptibility gene for lung cancer from currently available evidence. | 22215214 | 2012 |
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0.090 | GeneticVariation | BEFREE | Although the A1298C polymorphism was not associated with lung cancer risk, a significant interaction with drinking was observed. | 22024018 | 2011 |
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0.090 | GeneticVariation | BEFREE | As for A1298C polymorphism, there was no difference in distribution between the lung cancer</span> and control groups. | 20065319 | 2010 |
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0.090 | GeneticVariation | BEFREE | Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer. | 18789576 | 2009 |
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0.090 | GeneticVariation | BEFREE | The effect of MTHFR polymorphisms (C677T, A1298C) on the risk of lung cancer was undetectable, even though analyzed on a relatively good number of subjects (totally 11,526 subjects) by meta-analysis (statistical power = 93.9%). | 18340404 | 2008 |
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0.090 | GeneticVariation | BEFREE | However, we found no evidence for an association between the MTHFR C677T and A1298C polymorphisms and risk of lung cancer in either all of the subjects or the low folate intake subgroup; nor did we find evidence for an interaction between these two MTHFR polymorphisms and dietary folate intake or alcohol use. | 11319182 | 2001 |