Our results suggested that Arg399Gln variant of <i>XRCC1</i> gene might be a risk factor for NMSC in Asian populations, and Arg194Trp variant of <i>XRCC1</i> gene might be a protective factor for patients with SCC.
In the current study, we aim to assess the impact of XRCC1 R399Q and XRCC3 T241M polymorphisms on the risk of NMSC associated with sunlight and arsenic exposure.