Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs35749011
rs35749011 		G 0.700 GeneticVariation GWASCAT Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. 29263008

2018
dbSNP: rs616338
rs616338
ABI3
0.010 GeneticVariation BEFREE None of the other cohorts showed significant associations that were concordant with those for AD, although the DLB cohort had suggestive findings (Fisher's test: ABI3_rs616338-T OR = 1.79, p = 0.097; PLCG2_rs72824905-G OR = 0.32, p = 0.124). 30326945

2018
dbSNP: rs429358
rs429358
APOE
0.700 GeneticVariation GWASCAT GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study. 31065058

2019
dbSNP: rs429358
rs429358
APOE
C 0.700 GeneticVariation GWASCAT Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. 25188341

2014
dbSNP: rs429358
rs429358
APOE
C 0.700 GeneticVariation GWASCAT Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. 29263008

2018
dbSNP: rs1041833271
rs1041833271
APP
0.010 GeneticVariation BEFREE Neuropathologic and molecular studies in brains of carriers of the PSEN1 p.A396T mutation or other PSEN1 or PSEN2 mutations associated with the coexistence of DLBD and AD are needed to clarify whether tau and α-synuclein proteinopathies occur independently or whether a relationship exists between α-synuclein and tau that might explain the mechanisms of coaggregation. 31165862

2019
dbSNP: rs12734374
rs12734374
ASH1L
0.700 GeneticVariation GWASCAT GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study. 31065058

2019
dbSNP: rs897984
rs897984
BCL7C ; MIR4519 ; MIR762HG
0.700 GeneticVariation GWASCAT Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. 29263008

2018
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.010 GeneticVariation BEFREE To date, there have been several conflicting reports on the correlation between AD or PD and Val66Met or C270T polymorphism in the BDNF promoter region, although no data on this relationship have been published with respect to dementia with Lewy bodies (DLB). 16899999

2006
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.010 GeneticVariation BEFREE To date, there have been several conflicting reports on the correlation between AD or PD and Val66Met or C270T polymorphism in the BDNF promoter region, although no data on this relationship have been published with respect to dementia with Lewy bodies (DLB). 16899999

2006
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.010 GeneticVariation BEFREE We sought to determine whether the COMT val158met polymorphism (rs4680) is associated with delusions and hallucinations in people with dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). 23069674

2012
dbSNP: rs112176450
rs112176450
EIF4G1
0.010 GeneticVariation BEFREE Subsequent sequence and genotype analysis identified EIF4G1 c.1505C>T (p.Ala502Val), c.2056G>T (p.Gly686Cys), c.3490A>C (p.Ser1164Arg), c.3589C>T (p.Arg1197Trp) and c.3614G>A (p.Arg1205His) substitutions in affected subjects with familial parkinsonism and idiopathic Lewy body disease but not in control subjects. 21907011

2011
dbSNP: rs113388242
rs113388242
EIF4G1
0.010 GeneticVariation BEFREE Subsequent sequence and genotype analysis identified EIF4G1 c.1505C>T (p.Ala502Val), c.2056G>T (p.Gly686Cys), c.3490A>C (p.Ser1164Arg), c.3589C>T (p.Arg1197Trp) and c.3614G>A (p.Arg1205His) substitutions in affected subjects with familial parkinsonism and idiopathic Lewy body disease but not in control subjects. 21907011

2011
dbSNP: rs774457232
rs774457232
EIF4G1
0.010 GeneticVariation BEFREE Subsequent sequence and genotype analysis identified EIF4G1 c.1505C>T (p.Ala502Val), c.2056G>T (p.Gly686Cys), c.3490A>C (p.Ser1164Arg), c.3589C>T (p.Arg1197Trp) and c.3614G>A (p.Arg1205His) substitutions in affected subjects with familial parkinsonism and idiopathic Lewy body disease but not in control subjects. 21907011

2011
dbSNP: rs76763715
rs76763715
GBA
0.710 GeneticVariation BEFREE We have previously shown that the p.N370S variant in GBA is associated with DLB, which, together with the findings at the SCARB2 locus, suggests a role for lysosomal dysfunction in this disease. 24973356

2014
dbSNP: rs76763715
rs76763715
GBA
C 0.710 CausalMutation CLINVAR

dbSNP: rs104886460
rs104886460
GBA
T 0.700 CausalMutation CLINVAR

dbSNP: rs1064651
rs1064651
GBA
G 0.700 CausalMutation CLINVAR

dbSNP: rs75822236
rs75822236
GBA
T 0.700 CausalMutation CLINVAR

dbSNP: rs78973108
rs78973108
GBA
T 0.700 CausalMutation CLINVAR

dbSNP: rs80356769
rs80356769
GBA
A 0.700 CausalMutation CLINVAR

dbSNP: rs80356771
rs80356771
GBA
A 0.700 CausalMutation CLINVAR

dbSNP: rs1289324472
rs1289324472
GBA
0.010 GeneticVariation BEFREE We have previously shown that the p.N370S variant in GBA is associated with DLB, which, together with the findings at the SCARB2 locus, suggests a role for lysosomal dysfunction in this disease. 24973356

2014
dbSNP: rs421016
rs421016
GBA
0.010 GeneticVariation BEFREE The L444P mutation in the GBA1 gene which encodes β-glucocerebrosidase-1, is a major risk factor for developing Parkinson's disease (PD) and dementia with Lewy bodies (DLB). 31539859

2019
dbSNP: rs77369218
rs77369218
GBA
0.010 GeneticVariation BEFREE Age-related neurochemical and behavioural changes in D409V/WT GBA1 mouse: Relevance to lewy body dementia. 31299418

2019