Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.080 | GeneticVariation | BEFREE | Although the Val66Met polymorphism at the BDNF gene does not seem to play a significant role in children and adolescents with BD or ADHD, BDNF serum levels deserve further attention in future research on neurobiological aspects of BD and ADHD. | 27209073 | 2016 |
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0.080 | GeneticVariation | BEFREE | We performed both total sample and sex stratified analyses to investigate the effect of Val66Met genotype on the plasma BDNF levels, but only a trend of association was found in females with ADHD (n=84), with a tendency of lower plasma BDNF level in Val allele carriers than Met/Met genotype carriers (P=0.071). | 24713358 | 2014 |
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0.080 | GeneticVariation | BEFREE | We aimed to determine whether early parenting is associated with externalizing and internalizing symptoms in children with attention-deficit hyperactivity disorder (ADHD) and whether such an association is affected by the brain-derived neurotrophic factor (BDNF) val66met polymorphism. | 25425456 | 2014 |
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0.080 | GeneticVariation | BEFREE | The G/A genotype of the Val66Met SNP was associated with both ADHD and ID, and the G allele was significantly associated with ADHD. | 20943059 | 2010 |
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0.080 | GeneticVariation | BEFREE | No association between the p.Val66Met polymorphism and ADHD was found in any of the four populations or in the pooled sample. | 19603419 | 2010 |
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0.080 | GeneticVariation | BEFREE | No association was found between the Val66Met polymorphism and ADHD in either of the two populations. | 17044097 | 2007 |
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0.080 | GeneticVariation | BEFREE | We did not find support for an involvement of the Val66 allele of the Val66Met polymorphism of BDNF in the pathogenesis of ADHD in our sample. | 17219016 | 2007 |
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0.080 | GeneticVariation | BEFREE | The common Val66Met functional polymorphism in the human BDNF gene (rs 6265) was genotyped in a collaborative family-based sample of 341 white UK or Irish ADHD probands and their parents. | 15940292 | 2005 |