| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.700 | GeneticVariation | UNIPROT | A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants. | 22102614 | 2012 |
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|
0.700 | GeneticVariation | UNIPROT | Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants. | 21120944 | 2011 |
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|
0.700 | GeneticVariation | UNIPROT | Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue. | 14974087 | 2004 |
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|
0.700 | GeneticVariation | UNIPROT | Germline mutations in MLH1, MSH2 and MSH6 in Korean hereditary non-polyposis colorectal cancer families. | 15365995 | 2004 |
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|
0.700 | GeneticVariation | UNIPROT | Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene. | 12658575 | 2003 |
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|
0.700 | GeneticVariation | UNIPROT | A role for MLH3 in hereditary nonpolyposis colorectal cancer. | 11586295 | 2001 |
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|
0.700 | GeneticVariation | UNIPROT | Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer. | 10480359 | 1999 |
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|
0.700 | GeneticVariation | UNIPROT | Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations. | 10521294 | 1999 |
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|
0.700 | GeneticVariation | UNIPROT | Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. | 9354786 | 1997 |