Source: CLINVAR ×
Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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G | 0.700 | CausalMutation | CLINVAR | High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions. | 23658460 | 2013 |
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G | 0.700 | CausalMutation | CLINVAR | Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers. | 22430266 | 2012 |
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G | 0.700 | CausalMutation | CLINVAR | Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes. | 22703879 | 2012 |
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G | 0.700 | CausalMutation | CLINVAR | Predictive factors for BRCA1/BRCA2 mutations in women with ductal carcinoma in situ. | 22009639 | 2012 |
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G | 0.700 | CausalMutation | CLINVAR | Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. | 22006311 | 2011 |
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G | 0.700 | CausalMutation | CLINVAR | Reactive lymphoid hyperplasia in association with 22q11.2 deletion syndrome and a BRCA2 mutation. | 20887823 | 2011 |
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G | 0.700 | CausalMutation | CLINVAR | Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer. | 21324516 | 2011 |
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G | 0.700 | CausalMutation | CLINVAR | Founder BRCA1/2 mutations in the Europe: implications for hereditary breast-ovarian cancer prevention and control. | 23199084 | 2010 |
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G | 0.700 | CausalMutation | CLINVAR | Associations of high-grade prostate cancer with BRCA1 and BRCA2 founder mutations. | 19188187 | 2009 |
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G | 0.700 | CausalMutation | CLINVAR | Mouse embryonic stem cell-based functional assay to evaluate mutations in BRCA2. | 18607349 | 2008 |
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G | 0.700 | CausalMutation | CLINVAR | Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies. | 15994883 | 2005 |
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G | 0.700 | CausalMutation | CLINVAR | Functional evaluation and cancer risk assessment of BRCA2 unclassified variants. | 15695382 | 2005 |
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G | 0.700 | CausalMutation | CLINVAR | Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations. | 10570174 | 1999 |
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G | 0.700 | CausalMutation | CLINVAR | The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. | 9145676 | 1997 |
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G | 0.700 | CausalMutation | CLINVAR | Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer. | 8673092 | 1996 |
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G | 0.700 | CausalMutation | CLINVAR | BRCA2 germline mutations in male breast cancer cases and breast cancer families. | 8673091 | 1996 |