Disease: Multiple Sclerosis
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1801131
MTHFR
0.535 0.840 1 11794419 missense variant T/G snv 0.29 0.26 93
rs3184504
SH2B3 ; ATXN2
0.572 0.600 12 111446804 missense variant T/A;C;G snv 0.67 92
rs2070600
AGER
0.561 0.760 6 32183666 missense variant C/T snv 5.3E-02 3.6E-02 82
rs1061170
CFH
0.561 0.720 1 196690107 missense variant C/T snv 0.68 0.64 72
rs429358
APOE
0.590 0.600 19 44908684 missense variant T/C snv 0.14 0.16 66
rs7041
GC
0.576 0.800 4 71752617 missense variant A/C;T snv 0.52; 4.0E-06 64
rs1801275
IL4R
0.581 0.680 16 27363079 missense variant A/G snv 0.25 0.36 58
rs3918242
MMP9
0.602 0.680 20 46007337 upstream gene variant C/T snv 0.14 54
rs56149945
NR3C1
0.595 0.680 5 143399752 missense variant T/A;C snv 2.0E-02 49
rs7412
APOE
0.641 0.640 19 44908822 missense variant C/T snv 6.2E-02 7.9E-02 47
rs1979277
SHMT1
0.620 0.560 17 18328782 missense variant G/A snv 0.27 0.31 45
rs10757278
CDKN2B-AS1
0.620 0.520 9 22124478 intron variant A/G snv 0.40 44
rs1799969
ICAM1
0.637 0.560 19 10284116 missense variant G/A snv 0.11 9.3E-02 38
rs16139
NPY ; LOC107986777
0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02 36
rs1800206
PPARA
0.641 0.640 22 46218377 missense variant C/G snv 4.3E-02 4.2E-02 35
rs7799039
LOC105375494
0.649 0.560 7 128238730 upstream gene variant G/A;C snv 33
rs4977574
CDKN2B-AS1
0.695 0.520 9 22098575 intron variant A/G;T snv 26
rs12785878
NADSYN1
0.677 0.520 11 71456403 intron variant G/A;T snv 25
rs1799752
ACE
0.677 0.480 17 63488529 intron variant -/TTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCATACAGTCACTTTT delins 25
rs3087456
CIITA ; LOC105371080
0.742 0.480 16 10877045 intron variant G/A snv 0.53 14
rs1862513
RETN
0.763 0.360 19 7668907 upstream gene variant C/G;T snv 11
rs3761847
TRAF1
0.827 0.200 9 120927961 intron variant G/A snv 0.52 8
rs4774
CIITA
0.807 0.240 16 10906991 missense variant G/C snv 0.30 0.28 7