Disease: Lupus Erythematosus, Systemic
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs1800629
TNF
0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14 169
rs1800795
IL6-AS1 ; IL6 ; STEAP1B
0.494 0.840 7 22727026 intron variant C/G snv 0.71 140
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv 121
rs1801394
FASTKD3 ; MTRR
0.531 0.840 5 7870860 missense variant A/G snv 0.47 0.45 101
rs1801131
MTHFR
0.535 0.840 1 11794419 missense variant T/G snv 0.29 0.26 93
rs1800796
IL6-AS1 ; STEAP1B ; IL6
0.555 0.760 7 22726627 non coding transcript exon variant G/C snv 9.9E-02 74
rs11549465
HIF1A-AS3 ; HIF1A
0.597 0.680 14 61740839 missense variant C/T snv 8.8E-02 7.7E-02 55
rs5186
AGTR1
0.630 0.560 3 148742201 3 prime UTR variant A/C snv 0.23 0.21 38
rs4728142 0.732 0.320 7 128933913 upstream gene variant G/A snv 0.38 18
rs121908117
ATRIP ; TREX1 ; ATRIP-TREX1
0.708 0.440 3 48466707 missense variant G/A snv 17
rs1143679
ITGAM
0.732 0.520 16 31265490 missense variant G/A snv 9.7E-02 0.11 14
rs3764880
TLR8-AS1 ; TLR8
0.752 0.320 X 12906707 start lost A/G snv 0.31 0.30 11
rs315952
IL1RN
0.763 0.400 2 113132727 missense variant T/A;C snv 4.0E-06; 0.31 10
rs4740
EBI3
0.827 0.240 19 4236999 missense variant G/A snv 0.34 0.39 8
rs6677604
CFH
0.827 0.200 1 196717788 intron variant G/A snv 0.23 7
rs2248098
VDR
0.925 0.120 12 47859573 intron variant A/G;T snv 4
rs28362930
SEMA7A
0.925 0.160 15 74408859 downstream gene variant G/A snv 0.16 3
rs7704116
PPP2CA
1.000 0.080 5 134216763 intron variant C/T snv 9.9E-02 2