Disease: Impaired cognition
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1799945
LOC108783645 ; HFE
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10 226
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs1800795
IL6-AS1 ; IL6 ; STEAP1B
0.494 0.840 7 22727026 intron variant C/G snv 0.71 140
rs9939609
FTO
0.559 0.720 16 53786615 intron variant T/A snv 0.41 98
rs1229984
ADH1B
0.570 0.560 4 99318162 missense variant T/C;G snv 0.90 83
rs9340799
ESR1
0.583 0.680 6 151842246 intron variant A/G snv 0.32 62
rs4420638
APOC1
0.708 0.520 19 44919689 downstream gene variant A/G snv 0.18 43
rs746682028
BDNF ; BDNF-AS
0.645 0.480 11 27658414 missense variant C/A;T snv 4.0E-06; 4.0E-06 36
rs4925
GSTO1
0.677 0.560 10 104263031 missense variant C/A snv 0.25 0.23 28
rs375752214
NOS3
0.708 0.400 7 150998541 missense variant C/T snv 4.1E-06 4.2E-05 22
rs2072446
LOC100288866 ; MIR6165 ; NGFR
0.776 0.160 17 49510457 missense variant C/T snv 5.2E-02 4.1E-02 11
rs201118034
NOTCH3
0.827 0.200 19 15187315 missense variant G/A;C snv 3.2E-04; 4.0E-06 6
rs1256065
ESR2
0.925 0.120 14 64232214 3 prime UTR variant G/T snv 0.66 3