Disease: Multiple Sclerosis
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs34536443
TYK2
0.667 0.400 19 10352442 missense variant G/C snv 2.7E-02 2.8E-02 25
rs16944
IL1B
0.531 0.920 2 112837290 upstream gene variant A/G snv 0.57 92
rs10774671
OAS1
0.732 0.480 12 112919388 splice acceptor variant G/A;C snv 0.67 14
rs2476601
AP4B1-AS1 ; PTPN22
0.498 0.800 1 113834946 missense variant A/G snv 0.93 0.93 121
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06 223
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02 182
rs3135932
IL10RA
0.677 0.480 11 117993348 missense variant A/G snv 0.13 0.11 23
rs2069762
IL2
0.672 0.560 4 122456825 upstream gene variant A/C snv 0.24 23
rs2243250
IL4
0.570 0.760 5 132673462 upstream gene variant C/T snv 0.35 61
rs763059810
CXCR4
0.623 0.600 2 136115750 missense variant T/C snv 4.0E-06 41
rs2910164
MIR3142HG ; MIR146A
0.447 0.880 5 160485411 mature miRNA variant C/G snv 0.71; 4.1E-06 0.70 193
rs10936599
MYNN
0.637 0.600 3 169774313 synonymous variant C/T snv 0.29 0.21 32
rs1800872
IL19 ; IL10
0.495 0.840 1 206773062 5 prime UTR variant T/G snv 0.69 119
rs1800871
IL19 ; IL10
0.508 0.800 1 206773289 5 prime UTR variant A/G snv 0.69 108
rs1800896
IL19 ; IL10
0.507 0.800 1 206773552 intron variant T/C snv 0.41 113
rs17235409
SLC11A1
0.653 0.600 2 218395009 missense variant G/A;C snv 4.9E-02; 4.1E-06 31
rs1800795
IL6-AS1 ; IL6 ; STEAP1B
0.494 0.840 7 22727026 intron variant C/G snv 0.71 140
rs755622
MIF-AS1 ; MIF
0.611 0.720 22 23894205 intron variant G/C snv 0.26 44
rs1800629
TNF
0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14 169
rs422951
NOTCH4
0.807 0.280 6 32220606 missense variant T/C snv 0.40 0.40 8
rs2076530
TSBP1-AS1 ; BTNL2
0.724 0.640 6 32396039 missense variant T/C snv 0.42 0.40 17
rs7453920
HLA-DQB2
0.752 0.440 6 32762235 intron variant A/G;T snv 10
rs1024611 0.568 0.800 17 34252769 upstream gene variant A/G snv 0.28 63
rs3745274
CYP2B6
0.672 0.480 19 41006936 missense variant G/A;T snv 4.0E-06; 0.27 30
rs1799864
CCR2
0.572 0.680 3 46357717 missense variant G/A snv 0.13 0.12 68