DisGeNET - a database of gene-disease associations

List of shared variants

Malignant neoplasm of prostate, C0376358

Disease: Neoplastic Syndromes, Hereditary

Source: CURATED ×

Results per page

Gene

Disease

Variant

Source

DSI _v

DPI _v

pLI

Consequence

AF_EXOME

AF_GENOME

Variant	Gene	DSI _v	DPI _v	Chr	Position	Consequence	Alleles	Class	AF EXOME	AF GENOME	Num. diseases
rs141568342	CHEK2	1.000	0.080	22	28734532	missense variant	C/T	snv	1.6E-04	1.5E-04	2
rs80359540	BRCA2	0.925	0.080	13	32340176	frameshift variant	A/-	delins			3
rs121908702	CHEK2	0.882	0.120	22	28711986	stop gained	C/A;G;T	snv	8.0E-06; 4.0E-06; 7.6E-05		4
rs72552322	CHEK2	0.925	0.120	22	28725070	missense variant	C/T	snv	2.4E-05	7.0E-06	4
rs121908698	CHEK2	0.851	0.200	22	28725242	splice donor variant	C/A;T	snv	4.0E-06; 1.3E-04		7
rs200917541	CHEK2	0.851	0.200	22	28725270	stop gained	G/A;T	snv			5
rs560596101	CHEK2	0.851	0.200	22	28725241	splice donor variant	A/C;G;T	snv	4.0E-06		5
rs587781705	CHEK2	0.851	0.200	22	28734506	stop gained	A/C	snv			5
rs587782401	CHEK2	0.851	0.200	22	28734401	splice donor variant	A/G;T	snv	4.0E-06; 6.8E-05		5
rs730881701	CHEK2	0.827	0.200	22	28725278	stop gained	G/A;C	snv	2.4E-05	7.0E-06	5
rs138213197	HOXB13	0.701	0.240	17	48728343	missense variant	C/T	snv	1.8E-03	1.6E-03	8
rs45580035	BRCA2	0.790	0.240	13	32380043	missense variant	C/T	snv	1.2E-05		8
rs80359328	BRCA2	0.882	0.240	13	32336684	frameshift variant	-/A	delins			4
rs137853011	CHEK2	0.763	0.280	22	28695219	missense variant	G/A	snv	4.9E-04	2.6E-04	10
rs180177132	PALB2	0.790	0.280	16	23621362	stop gained	C/T	snv	6.0E-05	2.1E-05	8
rs397507327	BRCA2	0.776	0.280	13	32338598	stop gained	G/A;T	snv	4.1E-06		9
rs80358427	BRCA2	0.776	0.280	13	32332877	stop gained	A/T	snv	4.0E-06		10
rs80358807	BRCA2	0.763	0.280	13	32340146	stop gained	C/T	snv			9
rs80359584	BRCA2	0.807	0.280	13	32340757	frameshift variant	CTTAA/-	delins	4.2E-06	1.4E-05	8
rs397507404	BRCA2	0.763	0.320	13	32370955	splice acceptor variant	G/A;T	snv			10
rs41293511	BRCA2	0.763	0.320	13	32363369	missense variant	G/A;C	snv		7.0E-06	10
rs80358391	BRCA2	0.763	0.320	13	32319109	stop gained	G/A;T	snv	4.0E-06		10
rs80358557	BRCA2	0.763	0.320	13	32337464	stop gained	C/A;T	snv	4.0E-06; 4.0E-06		10
rs80358721	BRCA2	0.724	0.320	13	32339320	stop gained	C/A;G;R	snv	4.2E-06		11
rs80358893	BRCA2	0.763	0.320	13	32341011	stop gained	C/G	snv			10