Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1799945
LOC108783645 ; HFE
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10 226
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58 134
rs9939609
FTO
0.559 0.720 16 53786615 intron variant T/A snv 0.41 98
rs7903146
TCF7L2
0.554 0.680 10 112998590 intron variant C/G;T snv 93
rs780094
GCKR
0.658 0.400 2 27518370 intron variant T/C snv 0.67 62
rs1333049
CDKN2B-AS1
0.614 0.520 9 22125504 intron variant G/C snv 0.41 60
rs7412
APOE
0.641 0.640 19 44908822 missense variant C/T snv 6.2E-02 7.9E-02 47
rs964184
ZPR1
0.716 0.440 11 116778201 3 prime UTR variant G/C snv 0.82 47
rs174547
FADS2 ; FADS1
0.742 0.240 11 61803311 intron variant T/C snv 0.28 33
rs11066280
HECTD4
0.742 0.280 12 112379979 intron variant T/A snv 7.0E-03 27
rs5219
KCNJ11
0.701 0.360 11 17388025 stop gained T/A;C snv 0.64 25
rs247617 0.827 0.160 16 56956804 regulatory region variant C/A snv 0.29 20
rs765547 0.827 0.160 8 20008763 intergenic variant G/A;C;T snv 18
rs5068
NPPA ; NPPA-AS1 ; CLCN6
0.776 0.160 1 11845917 3 prime UTR variant A/G;T snv 13
rs757081
NUCB2
0.882 0.200 11 17330136 missense variant C/G snv 0.30 0.25 4
rs3757840
GCK
1.000 0.040 7 44191617 intron variant T/C;G snv 2