Disease: Geographic Atrophy
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1061170
CFH
0.561 0.720 1 196690107 missense variant C/T snv 0.68 0.64 72
rs429358
APOE
0.590 0.600 19 44908684 missense variant T/C snv 0.14 0.16 66
rs800292
CFH
0.645 0.560 1 196673103 missense variant G/A snv 0.32 0.40 33
rs10490924
ARMS2 ; LOC105378525
0.716 0.240 10 122454932 missense variant G/T snv 0.26 0.23 16
rs121913059
CFH
0.716 0.280 1 196747245 missense variant C/T snv 1.4E-04 1.9E-04 16
rs2070895
LIPC ; ALDH1A2
0.807 0.120 15 58431740 intron variant G/A snv 0.33 15
rs11200638
LOC105378525 ; HTRA1
0.724 0.280 10 122461028 non coding transcript exon variant G/A snv 0.23 14
rs17231506
CETP
0.851 0.040 16 56960616 upstream gene variant C/G;T snv 0.28 10
rs2230199
C3
0.763 0.240 19 6718376 missense variant G/C;T snv 0.15 10
rs9332739
CYP21A2 ; C2-AS1 ; C2
0.763 0.360 6 31936027 missense variant G/A;C snv 4.1E-06; 3.9E-02 10
rs10737680
CFH
0.827 0.080 1 196710325 intron variant A/C snv 0.44 9
rs2043085
ALDH1A2
0.827 0.080 15 58388755 intron variant T/C snv 0.54 9
rs2740488
ABCA1
0.827 0.120 9 104899461 intron variant A/C snv 0.29 9
rs10033900
CFI
0.807 0.040 4 109737911 intron variant T/C snv 0.54 7
rs641153
CFB ; CYP21A2
0.790 0.160 6 31946403 missense variant G/A;T snv 9.6E-02; 4.1E-06 7
rs10922109
CFH
0.827 0.080 1 196735502 intron variant C/A snv 0.46 6
rs1142
SRPK2
0.851 0.040 7 105115879 intron variant C/T snv 0.31 6
rs141853578
CFI
0.807 0.040 4 109764664 missense variant C/T snv 4.2E-04 3.9E-04 6
rs147859257
C3
0.827 0.040 19 6718135 missense variant T/G snv 2.8E-03 2.4E-03 6
rs570618
CFH
0.827 0.040 1 196687934 intron variant T/G snv 0.69 6
rs79037040
TNFRSF10A ; LOC389641
0.807 0.160 8 23225458 non coding transcript exon variant G/A;C;T snv 6
rs943080
LOC107986598
0.807 0.040 6 43858890 TF binding site variant C/T snv 0.61 6
rs11080055
TMEM97
0.851 0.040 17 28322698 intron variant A/C snv 0.54 5
rs114254831
PBX2
0.827 0.040 6 32187804 intron variant A/G snv 5
rs116503776
CYP21A2 ; SKIV2L
0.827 0.040 6 31962685 intron variant G/A snv 5